Within the framework of this collaborative research centre our team published many publications. All works are listed here for you.
Publications
Neurofilament Levels in Dendritic Spines Associate with Synaptic Status
Clara-Marie Gürth, Maira Augusta do Rego Barros Fernandes Lima, Victor Macarrón Palacios, Angel Rafael Cereceda Delgado, Jasmine Hubrich, Elisa D’Este (2023)
Published 15. March 2023
Cells
https://doi.org/10.3390/cells12060909
2023
Stress - Regulation of SUMO conjugation and of other Ubiquitin‐Like Modifiers
Dragana Ilic, Helge M.Magnussen, Marilyn Tirard (2022)
Published 23. December 2022
Sci Dir
https://doi.org/10.1016/j.semcdb.2021.12.010
Hsp multichaperone complex buffers pathologically modified Tau
Antonia Moll, Lisa Marie Ramirez, Momchil Ninov, Juliane Schwarz, Henning Urlaub, Markus Zweckstetter (2022)
Published 27. June 2022
Nat commun
https://doi.org/10.1038/s41467-022-31396-z
Colocalization of different neurotransmitter transporters on synaptic vesicles is sparse except for VGLUT1 and ZnT3
Neha Upmanyu, Jialin Jin, Henrik von der Emde, Marcelo Ganzella, Leon Bösche, Viveka Nand Malviya, Evi Zhuleku, Antonio Zaccaria Politi, Momchil Ninov, Ivan Silbern, Marcel Leutenegger, Henning Urlaub, Dietmar Riedel, Julia Preobraschenski, Ira Milosevic, Stefan W.Hell, Reinhard Jahn, Sivakumar Sambandan (2022)
Published 4. May 2022
Neuron
https://doi.org/10.1016/j.neuron.2022.02.008
ECM recycling as a novel plasticity mechanism with a potential role in disease
Tal Dankovich, Silvio O. Rizzoli (2022)
Published 31. March 2022
Front Cell Neurosci
https://doi.org/10.3389/fncel.2022.854897
The synaptic extracellular matrix: long-lived, stable, and still remarkably dynamic
Tal Dankovich, Silvio O. Rizzoli (2022)
Published 8. March 2022
Front Syn Neuro
https://doi.org/10.3389/fnsyn.2022.854956
White Matter Integrity Requires Continuous Myelin Synthesis at The Inner Tongue in Mice
Martin Meschkat, Anna M. Steyer, Marie-Theres Weil, Kathrin Kusch, Olaf Jahn, Lars Piepkorn, Paola Agüi-Gonzalez, Nhu Thi Ngoc Phan, Torben Ruhwedel, Boguslawa Sadowski, Silvio O. Rizzoli, Hauke B. Werner, Hannelore Ehrenreich, Klaus-Armin Nave, Wiebke Möbius (2022)
Published 4. March 2022
Nat commun
https://doi.org/10.1038/s41467-022-28720-y
Identification of distinct cytotoxic granules as the origin of supramolecular attack particles in T lymphocytes
Hsin-Fang Chang, Claudia Schirra, Momchil Ninov, Ulrike Hahn, Keerthana Ravichandran, Elmar Krause, Ute Becherer, Štefan Bálint, Maria Harkiolaki, Henning Urlaub, Salvatore Valitutti, Cosima T Baldari, Michael L Dustin, Reinhard Jahn, Jens Rettig (2022)
Published 24. February 2022
Nat commun
https://doi.org/10.1038/s41467-022-28596-y
Identification of distinct cytotoxic granules as the origin of supramolecular attack particles in T lymphocytes
Waja Wegner, Heinz Steffens, Carola Gregor, Fred Wolf, Katrin I Willig (2022)
Published 23. February 2022
eLife
https://doi.org/10.7554/eLife.73603
Ultrafast population coding and axo-somatic compartmentalization
Chenfei Zhang, David Hofmann, Andreas Neef, Fred Wolf (2022)
Published 18. January 2022
PLOS
https://doi.org/10.1371/journal.pcbi.1009775
2022
Extracellular matrix remodeling through endocytosis and resurfacing of Tenascin-R
Tal M. Dankovich, Rahul Kaushik, Linda HM Olsthoorn, Gabriel Cassinelli Petersen, Philipp Emanuel Giro, Verena Klüver, Paola Agüi-Gonzalez, Katharina Grewe, Guobin Bao, Sabine Beuermann, Hannah Abdul Hadi, Jose Dören, Simon Klöppner, Benjamin H. Cooper, Alexander Dityatev, Silvio O. Rizzoli (2021)
Published 8. December 2021
Pub Med
https://doi.org/10.1038/s41467-021-27462-7
Postnatal expression of the lysine methyltransferase SETD1B is essential for learning and the regulation of neuron-enriched genes
Alexandra Michurina, M. Sadman Sakib, Cemil Kerimoglu, Dennis Manfred Krüger, Lalit Kaurani, Md Rezaul Islam, Parth Devesh Joshi, Sophie Schröder, Tonatiuh Pena Centeno, Jiayin Zhou, Ranjiit Pradhan, Julia Cha, Xingbo Xu, Gregor Eichele, Elisabeth M. Zeisberg, Andrea Kranz, A. Francis Stewart, Andre Fischer (2021).
Published 22. November 2021
EMBO J
https://doi.org/10.15252/embj.2020106459
Heterogeneity of glutamatergic synapses: cellular mechanisms and network consequences
Carolin Wichmann, Thomas Kuner (2021)
Published 2. November 2021
Phys Rev
https://doi.org/10.1152/physrev.00039.2020
Photoactivatable Fluorescent Dyes with Hydrophilic Caging Groups and Their Use in Multicolor Nanoscopy
Alexey N. Butkevich, Michael Weber, Angel R. Cereceda Delgado, Lynn M. Ostersehlt, Elisa D’Este, Stefan W. Hell (2021)
Published 29. October 2021
ACS Pub
https://doi.org/10.1021/jacs.1c09999
Munc13-1 is a Ca(2+)-phospholipid-dependent vesicle priming hub that shapes synaptic short-term plasticity and enables sustained neurotransmission
Noa Lipstein, Shuwen Chang, Kun-Han Lin, Francisco Jose Lopez-Murcia, Erwin Neher, Holger Taschenberger, Nils Brose (2021).
Published 26. October 2021
Neuron
https://doi.org/10.1016/j.neuron.2021.09.054
Optimal Precision and Accuracy in 4Pi-STORM using Dynamic Spline PSF Models
Mark Bates, Jan Keller-Findeisen, Adrian Przybylski, Andreas Hüper, Till Stephan, Peter Ilgen, Angel R. Cereceda Delgado, Elisa D’Este, Stefan Jakobs, Steffen J. Sahl, Stefan W. Hell (2021)
Published 19. October 2021
BioRixV
https://doi.org/10.1101/2021.10.19.464803
A microRNA signature that correlates with cognition and is a target against cognitive decline
Md Rezaul Islam, Lalit Kaurani, Tea Berulava, Urs Heilbronner, Monika Budde, Tonatiuh Pena Centeno, Vakthang Elerdashvili, Maria-Patapia Zafieriou, Eva Benito, Sinem M Sertel, Maria Goldberg, Fanny Senner, Janos L Kalman, Susanne Burkhardt, Anne Sophie Oepen, Mohammad Sadman Sakib, Cemil Kerimoglu, Oliver Wirths, Heike Bickeböller, Claudia Bartels, Frederic Brosseron […] Andre Fischer (2021)
Published 11. October 2021
Embo mol
https://doi.org/10.15252/emmm.202013659
Exercise as a model to identify microRNAs linked to human cognition: a role for microRNA-409 and microRNA-501
Maria Goldberg, Md Rezaul Islam, Cemil Kerimoglu, Camille Lancelin, Verena Gisa, Susanne Burkhardt, Dennis M. Krüger, Till Marquardt, Berend Malchow, Andrea Schmitt, Peter Falkai, Farahnaz Sananbenesi, Andre Fischer (2021)
Published 8. October 2021
Trans Psych
https://doi.org/10.1038/s41398-021-01627-w
The mammalian rod synaptic ribbon is essential for Cavchannel facilitation and ultrafast synaptic vesicle fusion
Chad Grabner, Tobias Moser (2021)
Published 7. October 2021
eLife
https://doi.org/10.7554/elife.63844
Tubular microdomains of Rab7-endosomes retrieve TrkA, a mechanism disrupted in Charcot-Marie-Tooth 2B
Ronja Markworth, Vivian Dambeck, Lars Malte Steinbeck, Angeliki Koufali Bastian Bues, Tal M. Yankovich, Carolin Wichmann, Katja Burk (2021)
Published 23. August 2021
J Cell Sci
https://doi.org/10.1242/jcs.258559
RIM-Binding Protein 2 organizes Ca2+channel topography and regulates release probability and vesicle replenishment at a fast central synapse
Tanvi Butola, Theocharis Alvanos, Anika Hintze, Peter Koppensteiner, David Kleindienst, Ryuichi Shigemoto, Carolin Wichmann, Tobias Moser (2021)
Published 20. July 2021
BioRixV
https://doi.org/10.1101/2021.03.20.435607
Gold-Conjugated Nanobodies for Targeted Imaging Using High-Resolution Secondary Ion Mass Spectrometry
Paola Agüi-Gonzalez, Tal M. Dankovich, Silvio O. Rizzoli, Nhu T. N. Phan (2021)
Published 10. July 2021
DMPI NanoMat
https://doi.org/10.3390/nano11071797
A large-scale nanoscopy and biochemistry analysis of postsynaptic dendritic spines
Martin S. Helm, Tal M. Dankovich, Sunit Mandad, Burkhard Rammner, Sebastian Jähne, Vanessa Salimi, Christina Koerbs, Richard Leibrandt, Henning Urlaub, Thomas Schikorski, Silvio O. Rizzoli (2021)
Published 24. June 2021
Nat NeuroSci
https://doi.org/10.1038/s41593-021-00874-w
Low-Expressing Synucleinopathy Mouse Models Based on Oligomer-Forming Mutations and C-Terminal Truncation of α-Synuclein
Ana Martinez Hernandez, Ivan Silbern, Insa Geffers, Lars Tatenhorst, Stefan Becker, Henning Urlaub, Markus Zweckstetter, Christian Griesinger, Gregor Eichele (2021)
Published 17. June 2021
Front NeuroSci
https://doi.org/10.3389/fnins.2021.643391
Evaluation and Optimization of High-Field Asymmetric Waveform Ion-Mobility Spectrometry for Multiplexed Quantitative Site-Specific N-Glycoproteomics
Pan Fang, Yanlong Ji, Ivan Silbern, Rosa Viner, Thomas Oellerich, Kuan-Ting Pan*, Henning Urlaub (2021)
Published 16. June 2021
ACS Pub
https://doi.org/10.1021/acs.analchem.1c00802
Stable but not rigid: Chronic in vivo STED nanoscopy reveals extensive remodeling of spines, indicating multiple drivers of plasticity
Heinz Steffens, Alexander C. Mott , Siyuan Li, Waja Wegner, Pavel Švehla, Vanessa W. Y. Kan, Fred Wolf, Sabine Liebscher, Katrin I. Willig (2021)
Published 9. June 2021
Sci Adv
https://doi.org/10.1126/sciadv.abf2806
Correlative fluorescence microscopy, transmission electron microscopy and secondary ion mass spectrometry (CLEM-SIMS) for cellular imaging
Felix Lange, Paola Agüi-Gonzalez, Dietmar Riedel, Nhu T.N. Phan, Stefan Jakobs, Silvio O. Rizzoli (2021)
Published 10. May 2021
BioRxiv
https://doi.org/10.1371/journal.pone.0240768
Relative Quantification of Phosphorylated and Glycosylated Peptides from the Same Sample Using Isobaric Chemical Labelling with a Two-Step Enrichment Strategy
Ivan Silbern, Pan Fang, Yanlong Ji, Lenz Christof, Henning Urlaub, Kuan-Ting Pan (2021)
Published 6. May 2021
Springer
https://doi.org/10.1007/978-1-0716-1024-4_14
Secondary Ion Mass Spectrometry Imaging Reveals Changes in the Lipid Structure of the Plasma Membranes of Hippocampal Neurons following Drugs Affecting Neuronal Activity
Paola Agüi-Gonzalez, Bao Guobin, Maria A. Gomes de Castro, Silvio O. Rizzoli, and Nhu T. N. Phan (2021)
Published 26. April 2021
ACS Chem NeuroSci
https://doi.org/10.1021/acschemneuro.1c00031
Ultrastructural maturation of the endbulb of Held active zones comparing wild-type and otoferlin-deficient mice
Anika Hintze, Mehmet Gültas, Esther A. Semmelhack, Carolin Wichman (2021)
Published 23. April 2021
I Sci
https://doi.org/10.1016/j.isci.2021.102282
Exploring new roles for actin upon LTP induction in dendritic spines
Mayte Bonilla-Quintana, Florentin Wörgötter (2021)
Published 29. March 2021
Sci Rep
https://doi.org/10.1038/s41598-021-86367-z
RIM-Binding Proteins Are Required for Normal Sound-Encoding at Afferent Inner Hair Cell Synapses
Stefanie Krinner, Friederike Predoehl, Dinah Burfeind, Christian Vogl, Tobias Moser (2021)
Published 23. March 2021
Front Mol
https://doi.org/10.3389/fnmol.2021.651935
Challenges facing quantitative large-scale optical super-resolution, and some simple solutions
Tal M. Dankovich, Silvio O. Rizzoli (2021)
Published 19. March 2021
Sci Direct
https://doi.org/10.1016/j.isci.2021.102134
Presynaptic activity and protein turnover are correlated at the single-synapse level.
Sebastian Jähne, Fabian Mikulasch, Helge GH Heuer, Sven Truckenbrodt, Paola Agüi-Gonzalez, Katharina Grewe, Angela Vogts, Silvio O Rizzoli, Viola Priesemann (2021)
Published 16. March 2021
Cell Rep
https://doi.org/10.1016/j.celrep.2021.108841
Correction to: The Coding and Small Non-coding Hippocampal Synaptic RNAome.
Robert Epple, Dennis Krüger, Tea Berulava, Gerrit Brehm, Momchil Ninov, Rezaul Islam, Sarah Köster, Andre Fischer (2021)
Published 12. March 2021
Springer
https://doi.org/10.1007/s12035-021-02296-y
Memory consolidation and improvement by synaptic tagging and capture in recurrent neural networks
Jannik Luboeinski, Christian Tetzlaff (2021)
Published 3. March 2021
Comm Bio
https://doi.org/10.1038/s42003-021-01778-y
Reproducing Asymmetrical Spine Shape Fluctuations in a Model of Actin Dynamics Predicts Self-organized Criticality.
Mayte Bonilla-Quintana, Florentin Wörgötter, Elisa D’Este, Christian Tetzlaff, Michael Fauth (2021)
Published 17. February 2021
Sci Rep
https://doi.org/10.1038/s41598-021-83331-9
Monitoring mitochondrial translation in living cells.
Roya Yousefi, Eugenio F Fornasiero, Lukas Cyganek, Julio Montoya, Stefan Jakobs, Silvio O Rizzoli, Peter Rehling, David Pacheu-Grau (2021)
Published 15. February 2021
EMBO Rep
https://doi.org/10.1016/j.celrep.2021.108841
Protein phosphorylation in depolarized synaptosomes: Dissecting primary effects of calcium from synaptic vesicle cycling
Ivan Silbern, Kuan-Ting Pan, Maksims Fiosins, Stefan Bonn, Silvio O Rizzoli, Eugenio F Fornasiero, Henning Urlaub, Reinhard Jahn (2021)
Published 12. February 2021
Mol Cell Prot
https://doi.org/10.1016/j.celrep.2021.108841
The Coding and Small Non-coding Hippocampal Synaptic RNAome.
Robert Epple, Dennis Krüger, Tea Berulava, Gerrit Brehm, Momchil Ninov, Rezaul Islam, Sarah Köster, Andre Fischer (2021)
Published 10. February 2021
Springer
https://doi.org/10.1007/s12035-021-02296-y
Sulthiame impairs mitochondrial function in vitro and may trigger onset of visual loss in Leber hereditary optic neuropathy
Marie-Christine Reinert, David Pacheu Grau, Claudia B. Catarino, Thomas Klopstock, Andreas Ohlenbusch, Michael Schittkowski, Ekkehard Wilichowski , Peter Rehling, Knut Brockmann (2021)
Published 4. February 2021
Orphanet J
https://doi.org/10.1186/s13023-021-01690-y
Spatial clustering of orientation preference in primary visual cortex of the large rodent agouti
Dardo N Ferreiro, Sergioe A Conde-Ocazionez, João H.N Patriota, Luã C. Souza, Moacir F Oliveira, Fred Wolf, Kerstin E Schmidt (2020)
Published 22. January 2021
I Sci
https://doi.org/10.1016/j.isci.2020.101882
Exploring early time points of vimentin assembly in flow by fluorescence fluctuation spectroscopy
Eleonora Perego, Sarah Köster (2021)
Published 19. January 2021
J Lab on a Chip
https://doi.org/10.1039/D0LC00985G
Neuroligin-2 dependent conformational activation of Collybistin reconstituted in supported hybrid membranes
Jonas Schäfer, Lucas Förster, Ingo Mey, Theofilos Papadopoulos, Nils Brose, Claudia Steinem (2020b)
Published 13. January 2021
J Bio Chem
https://doi.org/10.1074/jbc.RA120.015347
NanoSIMS observations of mouse retinal cells reveal strict metabolic controls on nitrogen turnover
Elisa A Bonnin, Eugenio F Fornasiero, Felix Lange, Christoph W Turck, Silvio O Rizzoli (2021)
Published 5. January 2021
BMC Molecular and Cell Biology
https://doi.org/10.1186/s12860-020-00339-1
2021
A sensory cell diversifies its output by varying Ca2+ influx-release coupling among active zones
Özge D Özçete, Tobias Moser (2020)
Published 21. December 2020
EMBO J
https://doi.org/10.15252/embj.2020106010
Rho-Kinase Inhibition by Fasudil Modulates Presynaptic Vesicle Dynamics
Kim Ann Saal, Carmina Warth Pérez Arias, Anna‐Elisa Roser, Jan Christoph Koch, Mathias Bähr, Silvio O. Rizzoli, Paul Lingor (2020)
Published 20. December 2020
J Neurochem
https://doi.org/10.1111/jnc.15274
The mRNA-binding protein RBM3 regulates activity patterns and local synaptic translation in cultured hippocampal neurons
Sinem M. Sertel, Malena S. von Elling-Tammen, Silvio O. Rizzoli (2020)
Published 11. December 2020
J Neurosci
https://doi.org/10.1523/JNEUROSCI.0921-20.2020
Post-Translational Modifications Soften Vimentin IntermediateFilaments
Julia Kraxner, Charlotta Lorenz, Julia Menzel, Iwan Parfentev, Ivan Silbern, Manuela Denz, Henning Urlaub, Blanche Schwappach, Sarah Köster (2020)
Published 10. December 2020
Nanoscale
https://doi.org/10.1039/D0NR07322A
A minimalist model to measure interactions between proteins and synaptic vesicles
Eleonora Perego, Sofiia Reshetniak, Charlotta Lorenz, Christian Hoffmann, Dragomir Milovanović, Silvio O. Rizzoli, Sarah Köster (2020)
Published 3. December 2020
Scie Rep
https://doi.org/10.1038/s41598-020-77887-1
Spatial clustering of orientation preference in primary visual cortex of the large rodent agouti
Dardo N. Ferreiro, Sergio Conde-Ocazionez, João HN Patriota, Luã C Souza, Moacir F. Oliveira, Fred Wolf, Kerstin E. Schmidt (2020)
Published 1. December 2020
iSci
https://doi.org/10.1016/j.isci.2020.101882
Synaptic activity and strength are reflected by changes in the post-synaptic secretory pathway
Clara-Marie Gürth, Tal Dankovich, Silvio O. Rizzoli, Elisa D’Este (2020)
Published 25. November 2020
Sci Rep
https://doi.org/10.1038/s41598-020-77260-2
Neuropathology of patients with COVID-19 in Germany: a post-mortem case series
Jakob Matschke, Marc Lütgehetmann, Christian Hagel, Jan P Sperhake, Ann Sophie Schröder, Carolin Edler, Herbert Mushumba, Antonia Fitzek, Lena Allweiss, Maura Dandri, Matthias Dottermusch, Axel Heinemann, Susanne Pfefferle, Marius Schwabenland, Daniel Sumner Magruder, Stefan Bonn, Marco Prinz, Christian Gerloff, Klaus Püschel, Susanne Krasemann, Martin Aepfelbacher, Markus Glatzel (2020)
Published 21. October 2020
Lancet Neuro
https://doi.org/10.1016/S1474-4422(20)30308-2
A streamlined pipeline for multiplexed quantitative site-specific N-glycoproteomics
Pan Fang, Yanlong Ji, Ivan Silbern, Carmen Doebele, Momchil Ninov, Christof Lenz, Thomas Oellerich, Kuan-Ting Pan, Henning Urlaub (2020)
Published 19. October 2020
Nat Commun
https://doi.org/10.1038/s41467-020-19052-w
Increased expression of myelin-associated genes in frontal cortex of SNCA overexpressing rats and Parkinson's disease patients.
Thomas Hentrich, Zinah Wassouf, Christine Ehrhardt, Eva Haas, James D Mills, Eleonora Aronica, Tiago F. Outeiro, Jeannette Hübener-Schmid, Olaf Riess, Nicolas Casadei, Julia M Schulze-Hentrich (2020)
Published 5. October 2020
Aging (Albany NY)
https://doi.org/10.18632/aging.103935
Quantitative Synaptic Biology: A Perspective on Techniques, Numbers and Expectations.
SofiiaReshetniak , Ruben Fernández-Busnadiego, Marcus Müller, Silvio O. Rizzoli SO, Christian Tetzlaff (2020)
Published 2. October 2020
Int J Mol Sci
https://doi.org/10.1016/j.neuron.2020.09.004
Ultrastructural Imaging of Activity-Dependent Synaptic Membrane-Trafficking Events in Cultured Brain Slices
Cordelia Imig, Francisco José López-Murcia, Lydia Maus L, Ines H. García-Plaza, Lena S. Mortensen, Manuela Schwark, Valentin Schwarze, Julie Angibaud, U. Valentin Nägerl , Holger Taschenberger, Nils Brose, Benjamin H. Cooper (2020)
Published 28. September 2020
Neuron
https://doi.org/10.1016/j.neuron.2020.09.004
TIPPING THE SCALES: PEPTIDE-DEPENDENT DYSREGULATION OF NEURAL CIRCUIT DYNAMICS IN ALZHEIMER’S DISEASE
Samuel S. Harris, Fred Wolf, Bart De Strooper, Marcel Aurel Busche (2020)
Published 5. August 2020
Neuron
https://doi.org/10.1016/j.neuron.2020.06.005
Developmental GABA polarity switch and neuronal plasticity in Bioengineered Neuronal Organoids
Maira-Patapia Zafeiriou, Guobin Bao, James Hudson, Rashi Halder, Alica Blenkle, Mari-Kristin Schreiber, Andre Fischer, Detlev Schild, Wolfram-H.Zimmermann
(2020)
Published 29. July 2020
Nat Commun
https://doi.org/10.1038/s41467-020-17521-w
Deep-learning-based cell composition analysis from tissue expression profiles
Kevin Menden, Mohamed Marouf, Sergio Oller, Anupriya Dalmia, Karin Kloiber, Peter Heutink, Stefan Bonn (2020)
Published 22. July 2020
Sci Adv
https://doi.org/10.1126/sciadv.aba2619
Distinct mechanisms of over-representation of landmarks and rewards in the hippocampus
Sofiia Reshetniak, Jan-Eike Ußling, Eleonora Perego, Burkhard Rammner, Masaaki Sato, Kotaro Mizuta, Tanvir Islam, Masako Kawano, Yukiko Sekine, Takashi Takekawa, Daniel Gomez-Dominguez, Alexander Schmidt, Fred Wolf, Karam Kim, Hiroshi Yamakawa, Masamichi Ohkura, Min GooLee, Tomoki Fukai, Junichi Nakai, Yasunori Hayashi (2020)
Published 7. July 2020
Cell Reports
https://doi.org/10.1016/j.celrep.2020.107864
A comparative analysis of the mobility of 45 proteins in the synaptic bouton
Sofiia Reshetniak, Jan-Eike Ußling, Eleonora Perego, Burkhard Rammner, Thomas Schikorski, Eugenio F. Fornasiero, Sven Truckenbrodt, Sarah Köster, Silvio O. Rizzoli (2020).
Published 6. July 2020
EMBO J
https://doi.org/10.15252/embj.2020104596
A nanobody-based fluorescent reporter reveals human α-synuclein in the cell cyto-sol
Christoph Gerdes, Natalia Waal, Thomas Offner, Eugenio F Fornasiero, Nora Wender, Hannes Verbarg, Ivan Manzini, Claudia Trenkwalder, Brit Mollenhauer, Timo Strohäker, Markus Zweckstetter, Stefan Becker, Silvio O Rizzoli, Fitnat B. Basmanav, Felipe Opazo (2020).
Published 1. June 2020
Nat Commun
https://doi.org/10.1038/s41467-020-16575-0
PROTEIN TRAPPING LEADS TO ALTERED SYNAPTIC PROTEOSTASIS IN SYNUCLEINOPATHIES
Patricia D. Santos, Tiago F. Outerio (2020)
Published 13. May 2020
Febs J
https://doi.org/10.1111/febs.15364
X1INH, an improved next-generation affinity-optimized hydrazonic ligand, attenuates abnormal copper(i)/copper(ii)-α-Syn interactions and affects protein aggregation in a cellular model of synucleinopathy
Daphne S Cukierman, Diana F Lázaro, Pamela Sacco, Patricia R Ferreira, Renata Diniz , Claudio O Fernández, Tiago F Outeiro, Nicolas Rey (2020)
Published 11. May 2020
Dalton Trans
https://doi.org/10.1039/D0DT01138J
Circumvention of common labelling artefacts using secondary nanobodies
Shama Sograte-Idrissi, Thomas Schlichthaerle, Carlos Duque-Afonso, Mihai Alevra, Sebastian Strauss, Tobias Moser, Ralf Jungmann, Silvio O. Rizzoli, Felipe Opazo (2020)
Published 24. April 2020
Nanoscale
https://doi.org/10.1039/D0NR00227E
Vesicle adhesion in the electrostatic strong coupling regime studied by time-resolved small-angle x-ray scattering
Karlo Komorowski, Jannis Schaepper, Michael Sztucki, Lewis Sharpnack, Gerit Brehm, Sarah Köster, Tim Salditt (2020
Published 16. April 2020
Soft Matter
https://doi.org/10.1039/D0SM00259C
SUMOylation controls the neurodevelopmental function of the transcription factor Zbtb20
Silvia Ripamonti, Orr Schomroni, Jeong Seop Rhee, Kala Chowdhury, Olaf Jahn, Klaus P Hellmann, Stefan Bonn, Nils Brose, Marilyn Tirard (2020)
Published 31. March 2020
Nanoscale
https://doi.org/10.1111/jnc.15008
An experimentally generated pep-tide database increases the sensitivity of XL-MS with complex samples
Iwan Parfentev, Sandra Schilbach, Patrick Cramer, Henning Urlaub H (2020)
Published 19. March 2020
J Proteomics
https://doi.org/10.1016/j.jprot.2020.103754
Ultrastructural Correlates of Presynaptic Functional Heterogeneity in Hippocampal Synapses
Lydia Maus, ChoongKu Lee, Bekir Altas, Sinem M. Sertel, Kirsten Weyand, Silvio O. Rizzoli, Jeong Seop Rhee, Nils Brose, Cordelia Imig, Benjamin H. Cooper (2020)
Published 17. March 2020
Sci Direct
https://doi.org/10.1016/j.celrep.2020.02.083
Modeling the Shape of Synaptic Spines by Their Actin Dynamics
Mayte Bonilla-Quintana, Florentin Wörgötter, Christian Tetzlaff, Michael Fauth (2020)
Published 10. March 2020
Front Synaptic Neuroscience
https://doi.org/10.3389/fnsyn.2020.00009
The self-organized learning of noisy environmental stimuli re-quires distinct phases of plasticity
Steffen Krüppel, Christian Tetzlaff C (2020)
Published 1. March 2020
Net Neurosci
https://doi.org/10.1162/netn_a_00118
LIGHT MICROSCOPY OF MITOCHONDRIA AT THE NANOSCALE
Stefan Jakobs, Till Stephan, Peter Ilgen, Christian Brüser (2020)
Published 24. February 2020
Annu Rev BioPhys
https://doi.org/10.1146/annurev-biophys-121219-081550
Explainable Deep Learning for Augmentation of Small RNA Expression Profiles
Jelena Fiosina, Maksims Fiosins, Stefan Bonn (2020).
Published 6. February 2020
J of Comp Bio
https://doi.org/10.1089/cmb.2019.0320
Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors
Lin Luo, Mateusz C. Ambrozkiewicz, Fritz Benseler, Cui Chen, Emilie Dumontier, Susanne Falkner, Elisabetta Furlanis, Andrea M. Gomez, Naosuke Hoshina, …, NilsBrose, …, Matthijs Verhage, MichisukeYuzaki, Huda Yahya Zoghbi, Hiroshi Kawabe, Ann Marie Craig
Published 5. February 2020
Neuron
https:/doi.org/10.1016/j.neuron.2020.01.008
Kinetic coupling of the respiratory chain with ATP synthase, but not proton gradients, drives ATP production in cristae membranes
Alexandra Toth, Axel Meyrat, Stefan Stoldt, Ricardo Santiago, Dirk Wenzel, Stefan Jakobs , Christoph von Ballmoos, Martin Ott (2020)
Published 21. January 2020
PNAS
https://doi.org/10.1073/pnas.1917968117
EDITORIAL: PROTEIN MISFOLDING AND SPREADING PATHOLOGY IN NEURODEGENERATIVE DISEASES
Diana F. Lázaro, Arianna Bellucci, Patrik Brundin, Tiago F. Outeiro (2020)
Published 17. January 2020
Front Mol Neurosci
https://doi.org/10.3389/fnmol.2019.00312
Leaflet-dependent distribution of PtdIns`{`4,5`}`P2 in supported model membranes
Jonas Schäfer, Jessica Nehls, Markus Schön, Ingo P. Mey, Claudia Steinem (2020)
Published 17. January 2020
Langmuir
https://doi.org/10.1162/netn_a_00086
MINFLUX NANOSCOPY DELIVERS 3D MULTICOLOR NANOMETER RESOLUTION IN CELLS
Klaus C. Gwosch, Jasmin K. Pape, Francisco Balzarotti, Philipp Hoess, Jan Ellenberg, Jonas Ries, Stefan W.Hell (2020)
Published 13. January 2020
Nat Methods
https://doi.org/10.1038/s41592-019-0688-0
Realistic in silico generation and augmentation of single-cell RNA-seq data using generative adversarial networks
Mohamed Marouf, Pierre Machart, Vikas Bansal, Christoph Kilian, Daniel S. Magruder, Christian F. Krebs, Stefan Bonn (2020)
Published 9. January 2020
Nat Commun
https://doi.org/10.1038/s41467-019-14018-z
2020
The long noncoding RNA neuroLNC regulates presynaptic activity by interacting with the neurodegeneration-associated protein TDP-43
Sarva Keihani, Verena Kluever, Sunid Mandad, Vikas Bansal, Rahman R, Elisabeth Fritsch, Lucas Caldi Gomes, Annette Gärtner, Kügler S, Henning Urlaub, Jonathan D. Wren, Stefan Bonn, Silvio O. Rizzoli, Eugenio F. Fornasiero (2019)
Published 18. December 2019
Scie Adv
https://doi.org/10.1126/sciadv.aay2670
Mechanisms of alpha-synuclein toxicity: An update and outlook
Inês Caldeira Brás, Mary Xylaki, Tiago F. Outeiro (2019)
Published 23. November 2019
Porg Brain Res.
https://doi.org/10.1016/bs.pbr.2019.10.005
A mass spectrometry workflow for measuring protein turnover rates in vivo
Mihai Alevra, Sunit Mandad, Till Ischebeck, Henning Urlaub, Silvio O. Rizzoli*, Eugenio F. Fornasiero (2019) * corresponding author
Published 4. November 2019
Nat Protoc
https://doi.org/10.1038/s41596-019-0222-y
Are genetic and idiopathic forms of Parkinson's disease the same disease?
Leonor Correia Guedes, Tiago Mestre, Tiago F. Outeiro, Joaquim J. Ferreira (2019)
Published 23. October 2019
J Neurochem
https://doi.org/10.1111/jnc.14902
A combined miRNA-piRNA signature to detect Alzheimer's disease
Gaurav Jain, Anne Stuendl, Pooja Rao, Tea Berulava, Tonatiuh Pena Centeno, Lalit Kaurani, Susanne Burkhardt, Ivana Delalle, Johannes Kornhuber, Michael Hüll, Wolfgang Maier, Oliver Peters, Hermann Esselmann, Claudia Schulte, Christian Deuschle, Mathis Synofzik, Jens Wiltfang, Brit Mollenhauer, Walter Maetzler, Anja Schneider, Andre Fischer (2019)
Published 7. October 2019
Trans Psychiatry
https://doi.org/10.1038/s41398-019-0579-2
Live-cell STED nanoscopy of mitochondrial cristae
Till Stephan, Axel Roesch, Dietmar Riedel, Stefan Jakobs (2019)
Published 27. August 2019
Sci Rep
https://doi.org/10.1038/s41598-019-48838-2
In vitro models of synucleinopathies: informing on molecular mechanisms and protective strategies
Amir Tayaranian Marvian, David J. Koss, Farhang Aliakbari, Dina Morshedi, Tiago F. Outeiro (2019)
Published 23. August 2019
J Neurochem
https://doi.org/10.1111/jnc.14707
Synuclein Meeting 2019: where we are and where we need to go
Tiago F. Outeiro, Tiago A. Mestre (2019)
Published 23. August 2019
J Neurochem
https://doi.org/10.1111/jnc.14825
Interrogating Synaptic Architecture: Approaches for Labeling Organelles and Cytoskeleton Components
Sofiia Reshetniak, Silvio O. Rizzoli (2019)
Published 23. August 2019
Front Synaptic Neurosci
https://doi.org/10.3389/fnsyn.2019.00023
A2A R-induced transcriptional deregulation in astrocytes: An in vitro study
Isabel Paiva, Carvalho K, Santos P, Cellai L, Pavlou MAS, Jain G, Gnad T, Pfeifer A, Vieau D, Fischer A, Buée L, Outeiro TF, Blum D (2019)
Published 22. July 2019
PubMed
https://doi.org/10.1002/glia.23688
Correlative STED super-resolution light and electron microscopy on resin sections
Christian A. Wurm, Heinz Schwarz, Daniel C. Jans, Dietmar Riedel, Bruno M. Humbel, Stefan Jakobs (2019)
Published 16. July 2019
J Phys D: Appl Phys
https://doi.org/10.1088/1361-6463/ab2b31
Tagger – A Swiss army Knife for multiomics to dissect cell type-specific mechanisms of gene expression in mice
Lech Kaczmarczyk, Vikas Bansal, Ashish Rajput, Raza-ur Rahman, Wiesław Krzyżak, Joachim Degen, Stefanie Poll, Martin Fuhrmann, Stefan Bonn, Walker Scot Jackson (2019)
Published 8. August 2019
PLOS Biol
https://doi.org/10.1371/journal.pbio.3000374
Correlative STED super-resolution light and electron microscopy on resin sections.
Christian A Wurm, Heinz Schwarz, Daniel C. Jans, Dietmar Riedel, Bruno M Humbel, Stefan Jakobs (2019)
Published 16. July 2019
J Phys D Appl Phys
https://doi.org/10.1088/1361-6463/ab2b31
Cytosolic Trapping of a Mitochondrial Heat Shock Protein Is an Early Pathological Event in Synucleinopathies
Éva M. Szegő, Antonio Dominguez-Meijide, Ellen Gerhardt, Anne-Katrin König, David J. Koss, WenLi, Raquel Pinho, Christiane Fahlbusch, Mary Johnson, Patricia Santos, Anna Villar-Piqué, Tobias Thom, Silvio O. Rizzoli, Matthias Schmitz, Jiayi Li, Inga Zerr, Johannes Attems, Olaf Jahn, Tiago F. Outeiro (2019)
Published 2. July 2019
Cell Rep
https://doi.org/10.1016/j.celrep.2019.06.009
LRRK2, alpha-synuclein, and tau: partners in crime or unfortunate bystanders?
Tiago F. Outeiro, Kirsten Harvey, Antonio Dominguez-Meijide, Ellen Gerhardt (2019)
Published 28. June 2019
Biochem Soc Trans
https://doi.org/10.1042/BST20180466
SIMS imaging in neurobiology and cell biology
Paola Agüi-Gonzalez, Sebastian Jähne, Nhu T. Phan (2019)
Published 9. May 2019
JAAS
https://doi.org/10.1039/C9JA00118B
Translocator Protein Ligand Protects against Neurodegeneration in the MPTP Mouse Model of Parkinsonism
Gong J, Szego ÉM, Leonov A, Benito E, Becker S, Fischer A, Zweckstetter M, Outeiro T, Schneider A (2019)
Published 8. May 2019
J Neurosci
https://doi.org/10.1523/JNEUROSCI.2070-18.2019
A theoretical framework to derive simple, firing-rate-dependent mathematical models of synaptic plasticity
Janne Lappalainen, Juliane Herpich, Christian Tetzlaff (2019)
Published 8. May 2019
Front Comp Neuroscie
https://doi.org/10.3389/fncom.2019.00026
Principles underlying the input-dependent formation and organization of memories
Juliane Herpich, Christian Tetzlaff (2019)
Published 1. Mai 2019
Netw. Neurosci
https://doi.org/10.1162/netn_a_00086
Neuronal Redox-Imbalance in Rett Syndrome Affects Mitochondria as Well as Cytosol, and Is Accompanied by Intensified Mitochondrial O2 Consumption and ROS Release
Karolina Can, Christiane Menzfeld, Lena Rinne, Peter Rehling, Sebastian Kügler, Gocha Golubiani, Jan Dudek, Michael Müller (2019)
Published 30. April 2019
Front Physiol
https://doi.org/10.3389/fphys.2019.00479
Fluorinated nanobodies for targeted molecular imaging of biological samples using nanoscale secondary ion mass spectrometry
Selda Kabatas, Paola Agüi-Gonzalez, Rena Hinrichs, Sebastian Jähne, Felipe Opazo, Ulf Diederichsen, Silvio O. Rizzoli, Nhu T. N. Phan (2019)
Published 24. April 2019
JAAS
https://doi.org/10.1039/C9JA00117D
The role of LRRK2 in cell signaling
Kirsten Harvey, Tiago F. Outeiro (2019)
Published 28. February 2019
https://doi.org/10.1042/BST20180464
Seeding variability of different alpha synuclein strains in synucleinopathies
Niccolò Candelise, Matthias Schmitz, Franc Llorens, Anna Villar‐Piqué, Maria Cramm, Tobias Thom, Susana Margarida da Silva Correia, José Eriton Gomes da Cunha, Wiebke Möbius, Tiago F. Outeiro, Valentina González Álvarez, Martina Banchelli, Cristiano D’Andrea, Marella de Angelis, Saima Zafar, Alberto Rabano, Paolo Matteini, Inga Zerr (2019)
Published 22. February 2019
Ann Neurol
https://doi.org/10.1002/ana.25446
A practical guide to optimization in X10 expansion microscopy
Sven Truckenbrodt, Christoph Sommer, Silvio O. Rizzoli, Johann G. Danzl (2019)
Published 18. February 2019
Nat Protoc
https://doi.org/10.1038/s41596-018-0117-3
Biasing the native α-synuclein conformational ensemble towards compact states abolishes aggregation and neurotoxicity
Anita Carija, Francisca Pinheiro, Jordi Pujols, Inês C. Brás, Diana Fernandes Lázaro, Carlo Santambrogio, Rita Grandori,Tiago F.Outeiro, Susanna Navarro, Salvador Ventura (2019)
Published 5. February 2019
Redox Biol
https://doi.org/10.1016/j.redox.2019.101135
Boron-Containing Probes for Non-optical High-Resolution Imaging of Biological Samples
Selda Kabatas, Paola Agüi‐Gonzalez, Kim‐Ann Saal, Sebastian Jähne, Felipe Opazo, Silvio O. Rizzoli, Nhu T. N. Phan (2019)
Published 7. January 2019
Angew Chem Int Ed Engl
https://doi.org/10.1002/anie.201812032
Nuclear localization and phosphorylation modulate pathological effects of alpha-synuclein
Raquel Pinho, Isabel Paiva, Kristina Gotovac Jerčić, Luis Fonseca-Ornelas, Ellen Gerhardt, Christiane Fahlbusch, Paula Garcia-Esparcia, Cemil Kerimoglu, Maria A S Pavlou, Anna Villar-Piqué, Éva Szegő, Tomás Lopes da Fonseca, Francesca Odoardi, Szabolcs Soeroes, Ana Cristina Rego, Wolfgang Fischle, Jens C Schwamborn, Thomas Meyer, Sebastian Kügler, Isidre Ferrer, Johannes Attems, André Fischer, Stefan Becker, Markus Zweckstetter, Fran Borovecki, Tiago F. Outeiro (2019)
Published 1. January 2019
Hum Mol Genet
https://doi.org/10.1093/hmg/ddy326
2019
Nanobodies reveal an extra-syn-aptic population of SNAP-25 and Syntaxin 1A in hippocampal neurons
Manuel Maidorn, Aurélien Olichon, Silvio O. Rizzoli, Felipe Opazo (2019)
Published 28. December 2018
MAbs
https://doi.org/10.1080/19420862.2018.1551675
Combined Use of Unnatural Amino Acids Enables Dual Color Super-Resolution Imaging of Proteins via Click Chemistry
Kim-A. Saal, Frank Richter, Peter Rehling, Silvio O. Rizzoli (2018)
Published 10. December 2018
ACS Nano
https://doi.org/10.1021/acsnano.8b06047
Alpha-synuclein deregulates the expression of COL4A2 and impairs ER-Golgi function
Isabel Paiva, Gaurav Jain, Diana F. Lázaro, Kristina Gotovac Jerčić, Thomas Hentrich, Cemil Kerimoglu, Raquel Pinho, Èva M. Szegő, Susanne Burkhardt, Vincenzo Capece, Rashi Halder, Rezaul Islam, Mary Xylaki, Lucas A. Caldi Gomes, Anna-Elisa Roser, Paul Lingor, Julia M. Schulze-Hentrich, Fran Borovečki, Tiago F.Outeiro (2018)
Published November 2018
Epub
https://doi.org/10.1016/j.nbd.2018.08.001
Sensing α-Synuclein From the Outside via the Prion Protein: Implications for Neurodegeneration
Inês Caldeira Brás, Luisa V. Lopes, Tiago F. Outeiro
Published 13. November 2018
Epub
https://doi.org/10.1002/mds.27478
Precisely measured protein lifetimes in the mouse brain reveal biologically-significant differences across tissues and subcellular fractions
Eugenio F. Fornasiero, Sunit Mandad, Hanna Wildhagen, Mihai Alevra, Burkhard Rammner, Sarva Keihani, Felipe Opazo, Inga Urban, Till Ischebeck, M. Sadman Sakib, Maryam K. Fard, Koray Kirli, Tonatiuh Pena Centeno, Ramon O. Vidal, Raza-Ur Rahman, Eva Benito, André Fischer, Sven Dennerlein, Peter Rehling, Ivo Feussner, Stefan Bonn, Mikael Simons, Henning Urlaub, Silvio O. Rizzoli (2018)
Published 12. October 2018
Nat Commun
https://doi.org/10.1038/s41467-018-06519-0
Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents de generation of dopaminergic neurons
Jordi Pujols, Samuel Peña-Díaz, Diana F. Lázaro, Francesca Peccati, Francisca Pinheiro, Danilo González, Anita Carija, Susanna Navarro, María Conde-Giménez, Jesús García, Salvador Guardiola, Ernest Giralt, Xavier Salvatella, Javier Sancho, Mariona Sodupe, Tiago Fleming Outeiro, Esther Dalfó, Salvador Ventura (2018)
Published 24. September 2018
Proc Natl Acad Sci U S A
https://doi.org/10.1073/pnas.1804198115
Circulating miRNAs as Diagnostic Biomarkers for Parkinson's Disease
Anna Elisa Roser, Lucas Caldi Gomes, Jonas Schünemann, Fabian Maass, Paul Lingor (2018)
Published 5. September 2018
Front Neuro Scie
https://doi.org/10.3389/fnins.2018.00625
Membrane binding, internalization, and sorting of alpha-synuclein in the cell
Caterina Masaracchia, Marilena Hnida, Ellen Gerhardt, Tomás Lopes da Fonseca, Anna Villar-Pique,Tiago Branco, Markus A. Stahlberg, Camin Dean, Claudio O. Fernández, Ira Milosevic & Tiago F. Outeiro (2018)
Published 14. August 2018
Acta Neuropathol Commun
https://doi.org/10.1186/s40478-018-0578-1
Robust nanoscopy of a synaptic protein in living mice by organic-fluorophore labeling
Jennifer-Magdalena Masch, Heinz Steffens, Joachim Fischer, Johann Engelhardt, Jasmine Hubrich, Jan Keller-Findeisen, Elisa D’Este, Nicolai T. Urban, Seth G. N. Grant, Steffen J. Sahl, Dirk Kamin, Stefan W. Hell (2018)
Published 6. August 2018
Proc Natl Acad Sci U S A
https://doi.org/10.1073/pnas.1807104115
X10 expansion microscopy enables 25-nm resolution on conventional microscopes
Sven Truckenbrodt, Manuel Maidorn, Dagmar Crzan, Hanna Wildhagen, Selda Kabatas, Silvio O. Rizzoli (2018)
Published 10. July 2018
EMBO Rep
https://doi.org/10.15252/embr.201845836
Newly produced synaptic vesicle proteins are preferentially used in synaptic transmission
Sven Truckenbrodt, Abhiyan Viplav, Sebastian Jähne, Angela Vogts, Annette Denker, Hanna Wildhagen, Eugenio F.Fornasiero, Silvio O. Rizzoli (2018)
Published 27. June 2018
EMBO J
https://doi.org/10.15252/embj.201798044
SUMO1-conjugation is altered during normal aging but not by increased amyloid burden
Trayana Stankova, Lars Piepkorn, Thomas A. Bayer, Olaf Jahn, Marilyn Tirard (2018)
Published 6. April 2018
Aging Cell
https://doi.org/10.1111/acel.12760
WDR1 is a novel EYA3 substrate and its dephosphorylation induces modi-fications of the cellular actin cytoskeleton
Mihaela Mentel, Aura E. Ionescu, Ioana Puscalau-Girtu, Martin S. Helm, Rodica A. Badea, Silvio O. Rizzoli, Stefan E. Szedlacsek (2018)
Published 13. February 2018
Sci Rep
https://doi.org/10.1038/s41598-018-21155-w
2018
RIM-Binding Protein 2 Promotes a Large Number of CaV1.3 Ca2+-Channels and Contributes to Fast Synaptic Vesicle Replenishment at Hair Cell Active Zones
Stefanie Krinner, Tanvi Butola, SangYong Jung, Carolin Wichmann, Tobias Moser (2017)
Published 2. November 2017
Front Cell Neurosci
https://doi.org/10.3389/fncel.2017.00334
Piccolo Promotes Vesicle Replenishment at a Fast Central Auditory Synapse
Tanvi Butola, Carolin Wichmann, Tobias Moser (2017)
Published 25. October 2017
Front Synaptic Neurosci
https://doi.org/10.3389/fnsyn.2017.00014
2017