Publications

Within the framework of this collaborative research centre our team published many publications. All works are listed here for you.

Ultrastructural Correlates of Presynaptic Functional Heterogeneity in Hippocampal Synapses

Lydia Maus, ChoongKu Lee, Bekir Altas, Sinem M. Sertel, Kirsten Weyand, Silvio O. Rizzoli, Jeong Seop Rhee, Nils Brose, Cordelia Imig, Benjamin H. Cooper

Published: 17th March 2020

https://doi.org/10.1016/j.celrep.2020.02.083

Zur Publikation

Modeling the Shape of Synaptic Spines by Their Actin Dynamics

Mayte Bonilla-Quintana, Florentin Wörgötter, Christian Tetzlaff, Michael Fauth

Proved: 24th February 2020

Published: 10th March 2020

https://doi.org/10.3389/fnsyn.2020.00009

Zur Publikation

Leaflet-dependent distribution of PtdIns`{`4,5`}`P2 in supported model membranes

Jonas Schäfer, Jessica Nehls, Markus Schön, Ingo P. Mey, Claudia Steinem

Published: 17. January 2020
https://doi.org/10.1162/netn_a_00086

Zur Publikation

Realistic in silico generation and augmentation of single-cell RNA-seq data using generative adversarial networks

Mohamed Marouf, Pierre Machart, Vikas Bansal, Christoph Kilian, Daniel S. Magruder, Christian F. Krebs, Stefan Bonn

Received: 25. August 2018; Accepted: 13 December 2019;
Published: 9 January 2020

https://doi.org/10.1038/s41467-019-14018-z

Zur Publikation

2020

The long noncoding RNA neuroLNC regulates presynaptic activity by interacting with the neurodegeneration-associated protein TDP-43

Sarva Keihani, Verena Kluever, Sunid Mandad, Vikas Bansal, Rahman R, Elisabeth Fritsch, Lucas Caldi Gomes, Annette Gärtner, Kügler S, Henning Urlaub, Jonathan D. Wren, Stefan Bonn, Silvio O. Rizzoli, Eugenio F. Fornasiero (2019)

Published 18. December 2019

Scie Adv

https://doi.org/10.1126/sciadv.aay2670

Publication

Mechanisms of alpha-synuclein toxicity: An update and outlook

Inês Caldeira Brás, Mary Xylaki, Tiago F. Outeiro (2019)

Published 23. November 2019

Porg Brain Res.

https://doi.org/10.1016/bs.pbr.2019.10.005

Publication

A mass spectrometry workflow for measuring protein turnover rates in vivo

Mihai Alevra, Sunit Mandad, Till Ischebeck, Henning Urlaub, Silvio O. Rizzoli*, Eugenio F. Fornasiero (2019) * corresponding author

Published 4. November 2019

Nat Protoc

https://doi.org/10.1038/s41596-019-0222-y

Publication

Are genetic and idiopathic forms of Parkinson's disease the same disease?

Leonor Correia Guedes, Tiago Mestre, Tiago F. Outeiro, Joaquim J. Ferreira (2019)

Published 23. October 2019

J Neurochem

https://doi.org/10.1111/jnc.14902

Publication

A combined miRNA-piRNA signature to detect Alzheimer's disease

Gaurav Jain, Anne Stuendl, Pooja Rao, Tea Berulava, Tonatiuh Pena Centeno, Lalit Kaurani, Susanne Burkhardt, Ivana Delalle, Johannes Kornhuber, Michael Hüll, Wolfgang Maier, Oliver Peters, Hermann Esselmann, Claudia Schulte, Christian Deuschle, Mathis Synofzik, Jens Wiltfang, Brit Mollenhauer, Walter Maetzler, Anja Schneider, Andre Fischer (2019)

Published 7. October 2019

Trans Psychiatry

https://doi.org/10.1038/s41398-019-0579-2

Publication

Live-cell STED nanoscopy of mitochondrial cristae

Till Stephan, Axel Roesch, Dietmar Riedel, Stefan Jakobs (2019)

Published 27. August 2019

Sci Rep

https://doi.org/10.1038/s41598-019-48838-2

Publication

In vitro models of synucleinopathies: informing on molecular mechanisms and protective strategies

Amir Tayaranian Marvian, David J. Koss, Farhang Aliakbari, Dina Morshedi, Tiago F. Outeiro (2019)

Published 23. August 2019

J Neurochem

https://doi.org/10.1111/jnc.14707

Publication

Synuclein Meeting 2019: where we are and where we need to go

Tiago F. Outeiro, Tiago A. Mestre (2019)

Published 23. August 2019

J Neurochem

https://doi.org/10.1111/jnc.14825

Publication

Interrogating Synaptic Architecture: Approaches for Labeling Organelles and Cytoskeleton Components

Sofiia Reshetniak, Silvio O. Rizzoli (2019)

Published 23. August 2019

Front Synaptic Neurosci

https://doi.org/10.3389/fnsyn.2019.00023

Publication

Correlative STED super-resolution light and electron microscopy on resin sections

Christian A. Wurm, Heinz Schwarz, Daniel C. Jans, Dietmar Riedel, Bruno M. Humbel, Stefan Jakobs (2019)

Published 16. July 2019

J Phys D: Appl Phys

https://doi.org/10.1088/1361-6463/ab2b31

Publication

Tagger – A Swiss army Knife for multiomics to dissect cell type-specific mechanisms of gene expression in mice

Lech Kaczmarczyk, Vikas Bansal, Ashish Rajput, Raza-ur Rahman, Wiesław Krzyżak, Joachim Degen, Stefanie Poll, Martin Fuhrmann, Stefan Bonn, Walker Scot Jackson (2019)

Published 8. August 2019

 PLOS Biol

https://doi.org/10.1371/journal.pbio.3000374

Publication

Cytosolic Trapping of a Mitochondrial Heat Shock Protein Is an Early Pathological Event in Synucleinopathies

Éva M. Szegő, Antonio Dominguez-Meijide, Ellen Gerhardt, Anne-Katrin König, David J. Koss, WenLi, Raquel Pinho, Christiane Fahlbusch, Mary Johnson, Patricia Santos, Anna Villar-Piqué, Tobias Thom, Silvio O. Rizzoli, Matthias Schmitz, Jiayi Li, Inga Zerr, Johannes Attems, Olaf Jahn, Tiago F. Outeiro (2019)

Published 2. July 2019

Cell Rep

https://doi.org/10.1016/j.celrep.2019.06.009

Publication

LRRK2, alpha-synuclein, and tau: partners in crime or unfortunate bystanders?

Tiago F. Outeiro, Kirsten Harvey, Antonio Dominguez-Meijide, Ellen Gerhardt (2019)

Published 28. June 2019

Biochem Soc Trans

https://doi.org/10.1042/BST20180466

Publication

SIMS imaging in neurobiology and cell biology

Paola Agüi-Gonzalez, Sebastian Jähne, Nhu T. Phan (2019)

Published 9. May 2019

JAAS

https://doi.org/10.1039/C9JA00118B

Publication

A theoretical framework to derive simple, firing-rate-dependent mathematical models of synaptic plasticity

Janne Lappalainen, Juliane Herpich, Christian Tetzlaff (2019)

Published 8. May 2019

Front Comp Neuroscie

https://doi.org/10.3389/fncom.2019.00026

Publication

Principles underlying the input-dependent formation and organization of memories

Juliane Herpich, Christian Tetzlaff (2019)

Published 1. Mai 2019

Netw. Neurosci

https://doi.org/10.1162/netn_a_00086

Publication

Neuronal Redox-Imbalance in Rett Syndrome Affects Mitochondria as Well as Cytosol, and Is Accompanied by Intensified Mitochondrial O2 Consumption and ROS Release

Karolina Can, Christiane Menzfeld, Lena Rinne, Peter Rehling, Sebastian Kügler, Gocha Golubiani, Jan Dudek, Michael Müller (2019)

Published 30. April 2019

Front Physiol

https://doi.org/10.3389/fphys.2019.00479

Publication

Fluorinated nanobodies for targeted molecular imaging of biological samples using nanoscale secondary ion mass spectrometry

Selda Kabatas, Paola Agüi-Gonzalez, Rena Hinrichs, Sebastian Jähne, Felipe Opazo, Ulf Diederichsen, Silvio O. Rizzoli, Nhu T. N. Phan (2019)

Published 24. April 2019

JAAS

https://doi.org/10.1039/C9JA00117D

Publication

The role of LRRK2 in cell signaling

Kirsten Harvey, Tiago F. Outeiro (2019)

Published 28. February 2019

https://doi.org/10.1042/BST20180464

Publication

Seeding variability of different alpha synuclein strains in synucleinopathies

Niccolò Candelise, Matthias Schmitz, Franc Llorens, Anna Villar‐Piqué, Maria Cramm, Tobias Thom, Susana Margarida da Silva Correia, José Eriton Gomes da Cunha, Wiebke Möbius, Tiago F. Outeiro, Valentina González Álvarez, Martina Banchelli, Cristiano D’Andrea, Marella de Angelis, Saima Zafar, Alberto Rabano, Paolo Matteini, Inga Zerr (2019)

Published 22. February 2019

Ann Neurol

https://doi.org/10.1002/ana.25446

Publication

A practical guide to optimization in X10 expansion microscopy

Sven Truckenbrodt, Christoph Sommer, Silvio O. Rizzoli, Johann G. Danzl (2019)

Published 18. February 2019

Nat Protoc

https://doi.org/10.1038/s41596-018-0117-3

Publication

Biasing the native α-synuclein conformational ensemble towards compact states abolishes aggregation and neurotoxicity

Anita Carija, Francisca Pinheiro, Jordi Pujols, Inês C. Brás, Diana Fernandes Lázaro, Carlo Santambrogio, Rita Grandori,Tiago F.Outeiro, Susanna Navarro, Salvador Ventura (2019)

Published 5. February 2019

Redox Biol

https://doi.org/10.1016/j.redox.2019.101135

Publication

Boron-Containing Probes for Non-optical High-Resolution Imaging of Biological Samples

Selda Kabatas, Paola Agüi‐Gonzalez, Kim‐Ann Saal, Sebastian Jähne, Felipe Opazo, Silvio O. Rizzoli, Nhu T. N. Phan (2019)

Published 7. January 2019

Angew Chem Int Ed Engl

https://doi.org/10.1002/anie.201812032

Publication

Nuclear localization and phosphorylation modulate pathological effects of alpha-synuclein

Raquel Pinho, Isabel Paiva, Kristina Gotovac Jerčić, Luis Fonseca-Ornelas, Ellen Gerhardt, Christiane Fahlbusch, Paula Garcia-Esparcia, Cemil Kerimoglu, Maria A S Pavlou, Anna Villar-Piqué, Éva Szegő, Tomás Lopes da Fonseca, Francesca Odoardi, Szabolcs Soeroes, Ana Cristina Rego, Wolfgang Fischle, Jens C Schwamborn, Thomas Meyer, Sebastian Kügler, Isidre Ferrer, Johannes Attems, André Fischer, Stefan Becker, Markus Zweckstetter, Fran Borovecki, Tiago F. Outeiro (2019)

Published 1. January 2019

Hum Mol Genet

https://doi.org/10.1093/hmg/ddy326

Publication

2019

Nanobodies reveal an extra-syn-aptic population of SNAP-25 and Syntaxin 1A in hippocampal neurons

Manuel Maidorn, Aurélien Olichon, Silvio O. Rizzoli, Felipe Opazo (2019)

Published 28. December 2018

MAbs

https://doi.org/10.1080/19420862.2018.1551675

Publication

Combined Use of Unnatural Amino Acids Enables Dual Color Super-Resolution Imaging of Proteins via Click Chemistry

Kim-A. Saal, Frank Richter, Peter Rehling, Silvio O. Rizzoli (2018)

Published 10. December 2018

ACS Nano

https://doi.org/10.1021/acsnano.8b06047

Publication

Alpha-synuclein deregulates the expression of COL4A2 and impairs ER-Golgi function

Isabel Paiva, Gaurav Jain, Diana F. Lázaro, Kristina Gotovac Jerčić, Thomas Hentrich, Cemil Kerimoglu, Raquel Pinho, Èva M. Szegő, Susanne Burkhardt, Vincenzo Capece, Rashi Halder, Rezaul Islam, Mary Xylaki, Lucas A. Caldi Gomes, Anna-Elisa Roser, Paul Lingor, Julia M. Schulze-Hentrich, Fran Borovečki, Tiago F.Outeiro (2018)

Published November 2018

Epub

https://doi.org/10.1016/j.nbd.2018.08.001

Publication

Sensing α-Synuclein From the Outside via the Prion Protein: Implications for Neurodegeneration

Inês Caldeira Brás, Luisa V. Lopes, Tiago F. Outeiro

Published 13. November 2018

Epub

https://doi.org/10.1002/mds.27478

Publication

Precisely measured protein lifetimes in the mouse brain reveal biologically-significant differences across tissues and subcellular fractions

Eugenio F. Fornasiero, Sunit Mandad, Hanna Wildhagen, Mihai Alevra, Burkhard Rammner, Sarva Keihani, Felipe Opazo, Inga Urban, Till Ischebeck, M. Sadman Sakib, Maryam K. Fard, Koray Kirli, Tonatiuh Pena Centeno, Ramon O. Vidal, Raza-Ur Rahman, Eva Benito, André Fischer, Sven Dennerlein, Peter Rehling, Ivo Feussner, Stefan Bonn, Mikael Simons, Henning Urlaub, Silvio O. Rizzoli (2018)

Published 12. October 2018

Nat Commun

https://doi.org/10.1038/s41467-018-06519-0

Publication

Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents de generation of dopaminergic neurons

Jordi Pujols, Samuel Peña-Díaz, Diana F. Lázaro, Francesca Peccati, Francisca Pinheiro, Danilo González, Anita Carija, Susanna Navarro, María Conde-Giménez, Jesús García, Salvador Guardiola, Ernest Giralt, Xavier Salvatella, Javier Sancho, Mariona Sodupe, Tiago Fleming Outeiro, Esther Dalfó, Salvador Ventura (2018)

Published 24. September 2018

Proc Natl Acad Sci U S A

https://doi.org/10.1073/pnas.1804198115

Publication

Circulating miRNAs as Diagnostic Biomarkers for Parkinson's Disease

Anna Elisa Roser, Lucas Caldi Gomes, Jonas Schünemann, Fabian Maass, Paul Lingor (2018)

Published 5. September 2018

Front Neuro Scie

https://doi.org/10.3389/fnins.2018.00625

Publication

Membrane binding, internalization, and sorting of alpha-synuclein in the cell

Caterina Masaracchia, Marilena Hnida, Ellen Gerhardt, Tomás Lopes da Fonseca, Anna Villar-Pique,Tiago Branco, Markus A. Stahlberg, Camin Dean, Claudio O. Fernández, Ira Milosevic & Tiago F. Outeiro (2018)

Published 14. August 2018

Acta Neuropathol Commun

https://doi.org/10.1186/s40478-018-0578-1

Publication

Robust nanoscopy of a synaptic protein in living mice by organic-fluorophore labeling

Jennifer-Magdalena Masch, Heinz Steffens, Joachim Fischer, Johann Engelhardt, Jasmine Hubrich, Jan Keller-Findeisen, Elisa D’Este, Nicolai T. Urban, Seth G. N. Grant, Steffen J. Sahl, Dirk Kamin, Stefan W. Hell (2018)

Published 6. August 2018

Proc Natl Acad Sci U S A

https://doi.org/10.1073/pnas.1807104115

Publication

X10 expansion microscopy enables 25-nm resolution on conventional microscopes

Sven Truckenbrodt, Manuel Maidorn, Dagmar Crzan, Hanna Wildhagen, Selda Kabatas, Silvio O. Rizzoli  (2018)

Published 10. July 2018

EMBO Rep

https://doi.org/10.15252/embr.201845836

Publication

Newly produced synaptic vesicle proteins are preferentially used in synaptic transmission

Sven Truckenbrodt, Abhiyan Viplav, Sebastian Jähne, Angela Vogts, Annette Denker, Hanna Wildhagen, Eugenio F.Fornasiero, Silvio O. Rizzoli (2018)

Published 27. June 2018

EMBO J

https://doi.org/10.15252/embj.201798044

Publication

SUMO1-conjugation is altered during normal aging but not by increased amyloid burden

Trayana Stankova, Lars Piepkorn, Thomas A. Bayer, Olaf Jahn, Marilyn Tirard (2018)

Published 6. April 2018

Aging Cell

https://doi.org/10.1111/acel.12760

Publication

WDR1 is a novel EYA3 substrate and its dephosphorylation induces modi-fications of the cellular actin cytoskeleton

Mihaela Mentel, Aura E. Ionescu, Ioana Puscalau-Girtu, Martin S. Helm, Rodica A. Badea, Silvio O. Rizzoli, Stefan E. Szedlacsek (2018)

Published 13. February 2018

Sci Rep

https://doi.org/10.1038/s41598-018-21155-w

Publication

2018

RIM-Binding Protein 2 Promotes a Large Number of CaV1.3 Ca2+-Channels and Contributes to Fast Synaptic Vesicle Replenishment at Hair Cell Active Zones

Stefanie Krinner, Tanvi Butola, SangYong Jung, Carolin Wichmann, Tobias Moser (2017)

Published 2. November 2017

Front Cell Neurosci

https://doi.org/10.3389/fncel.2017.00334

Publication

Piccolo Promotes Vesicle Replenishment at a Fast Central Auditory Synapse

Tanvi Butola, Carolin Wichmann, Tobias Moser (2017)

Published 25. October 2017

Front Synaptic Neurosci

https://doi.org/10.3389/fnsyn.2017.00014

Publication

2017
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