Publications

Within the framework of this collaborative research centre our team published many publications. All works are listed here for you.

The lack of synapsin alters presynaptic plasticity at hippocampal mossy fibers in male mice

Felicitas Bruentgens, Laura Moreno Velasquez, Alexander Stumpf, Daniel Parthier, Jörg Breustedt, Fabio Benfenati, Dragomir Milovanovic, Dietmar Schmitz, Marta Orlando (2024)
Published 12. June 2024
Eneuro
https://doi.org/10.1523/ENEURO.0330-23.2024

Publication

Transient pores in hemifusion diaphragms

Russell Spencer, Yuliya Smirnova, Alireza Soleimani, Marcus Müller (2024)
Published 11. June 2024
Bio Phys
https://doi.org/10.1016/j.bpj.2024.06.009

Publication

Nanobodies against the myelin enzyme CNPase as tools for structural and functional studies

Sigurbjörn Markusson, Arne Raasakka, Marcel Schröder, Shama Sograte-Idrissi, Amir Mohammad Rahimi, Ommolbanin Asadpour, Henrike Körner, Dmitri Lodygin, Maria A. Eichel-Vogel, Risha Chowdhury, Aleksi Sutinen, Manasi Iyer, Madeline H. Cooper, Maya K. Weigel, Nicholas Ambiel, Hauke B. Werner, J. Bradley Zuchero, Felipe Opazo, Petri Kursul (2024)
Published 1. June 2024
BioRxiv
https://doi.org/10.1101/2024.05.25.595513

Publication

Impact of Phosphorylation on the Structural Ensemble of alpha-Synuclein in Aqueous Solution

Anton Emil Dorn, Emile de Bruyn, Giulia Rossetti, Claudio Fernandez, Tiago F. Outeiro, Jörg B. Schulz, Paolo Carloni (2024)
Published 24. May 2024
BioRxiv
http://dx.doi.org/10.1101/2023.03.10.531864

Publication

Coordinating mitochondrial translation with assembly of the OXPHOS complexe

Laura S Kremer, Peter Rehling (2024)
Published 23. May 2024
Hum Mol Gen
https://doi.org/10.1093/hmg/ddae025

Publication

Integrative Analysis of miRNA Expression Profiles Reveals Distinct and Common Molecular Mechanisms Underlying Broad Diagnostic Groups of Severe Mental Disorders

Jeremie Poschmann, Pierre Solomon, Lalit Kaurani, Monika Budde …. Andre Fischer, Urs Helbronner (2024)

Published 3. May 2024
Res Square
https://doi.org/10.21203/rs.3.rs-4279982/v1

Publication

An aldehyde-crosslinking mitochondrial probe for STED imaging in fixed cells

Jingting Chen, Till Stephan, Felix Gaedke, Tianyan Liu, Yiyan Li, Astrid Schauss, Peng Chen, Veronika Wulff, Stefan Jakobs, Christian Jüngst, Zhixing Chen (2024)
Published 30. April 2024
PNAS

https://www.pnas.org/doi/full/10.1073/pnas.2317703121

Publication

DISSECT: deep semi-supervised consistency regularization for accurate cell type fraction and gene expression estimation

Robin Khatri, Pierre Machart, Stefan Bonn (2024)
Published 30. April 2024
BMC

https://doi.org/10.1186/s13059-024-03251-5

Publication

Different states of synaptic vesicle priming explain target cell type–dependent differences in neurotransmitter release

Mohammad Aldahabi, Erwin Neher, Zoltan Nusser (2024)
Published 24. April 2024
PNAS

https://doi.org/10.1073/pnas.2322550121

Publication

A role for astrocytic miR-129-5p in Frontotemporal Dementia.

Lalit Kaurani, Ranjit Pradhan, Sophie Schröder, Susanne Burkhardt, Anna-Lena Schuetz,  Dennis M. Krüger,  Tonatiuh Pena, Peter Heutink, Farahnaz Sananbenesi, Andre Fischer (2024)
Published 19. April 2024
BioRxiv

https://doi.org/10.1101/2024.04.15.589528

Publication

α-Synuclein triggers cofilin pathology and dendritic spine impairment via a PrPC-CCR5 dependent pathway

Marina I. Oliveira da Silva, Miguel Santejo, Isaac W. Babcock, Ana Magalhaes, Lauria S. Minamide, Seok Joon Won, Erika Castillo, Ellen Gerhardt, Christiane Fahlbuch, Raymond A. Swanson, Tiago F. Outeiro, Ricardo Taipa, Michael Ruff, James R. Bamburg, Marcia A. Liz (2024)
Published 13. April 2024

Cell Death Dis

https://doi.org/10.1038/s41419-024-06630-9

Publication

Three-dimensional multi-target super-resolution microscopy of cells using Metal-Induced Energy Transfer and DNA-PAINT

Nazar Oleksiievets, Mougios, Daniel C. Jans, Lara Hauke, Jan Christoph Thiele, Samrat Basak, Stefan Jakobs, Felipe Opazo, Jörg Enderlein, Roman Tsukanov (2024)
Published 3. April 2024

BioRxiv

https://doi.org/10.1101/2024.04.02.587536

Publication

Complexin has a dual synaptic function as checkpoint protein in vesicle priming and as a promoter of vesicle fusion

Francisco José López-Murcia, Kun-Han Lin, Manon M. M. Berns, Mrinalini Ranjan, Noa Lipstein, Erwin Neher, Nils Brose, Kerstin Reim, Holger Taschenberger (2024)
Published 3. April 2024

PNAS

ttps://doi.org/10.1073/pnas.2320505121

Publication

Membrane fission via transmembrane contact

Russel K.W. Spencer, Isaac Santos-Perez, Izaro Rodrigues-Renovales, Juan Manuel Martinez Galvez, Anna V. Shnyrova, Marcus Müller (2024)
Published 30. March 2024

Nature Com

https://doi.org/10.1038/s41467-024-47122-w

Publication

Spatial proteomics in neurons at single-protein resolution

Eduard M. Unterauer, Sayedali Shetab Boushehri, Kristina Jevdokimenko, Luciano A. Masullo, Mahipal Ganji, Shama Sograte-Idrissi, Rafal Kowalewsk, Sebastian Strauss, Susanne C.M. Reinhardt, Ana Perovic, Carsten Mar, Felipe Opazo, Eugenio F. Fornasiero, Ralf Jungmann (2024)
Published 28. March 2024
Sci Dir

https://doi.org/10.1016/j.cell.2024.02.045

Publication

Formation of memory assemblies through the DNA-sensing TLR9 pathway

Vladimir Jovasevic, Elizabeth M. Wood, Ana Cicvaric, Hui Zhang, Zorica Petrovic, Anna Carboncino, Kendra K. Parker, Thomas E. Bassett, Maria Moltesen, Naoki Yamawaki, Hande Login, Joanna Kalucka, Farahnaz Sananbenesi,Xusheng Zhang, Andre Fischer, Jelena Radulovic (2024)
Published 27. March 2024
Nature

https://doi.org/10.1038/s41586-024-07220-7

Publication

Dynamic Gain Decomposition Reveals Functional Effects of Dendrites, Ion Channels, and Input Statistics in Population Coding

Chenfei Zhang, Omer Revah, Fred Wolf, Andreas Neef (2024)
Published 27. March 2024
J NeuroSci

https://dx.doi.org/10.1523/jneurosci.0799-23.2023

Publication

Regulation of Zbp1 by miR-99b-5p in microglia controls the development of schizophrenia-like symptoms in mice

Lalit Kaurani, Md Rezaul Islam, Urs Heilbronner, Dennis M Krüger, Jiayin Zhou, Aditi Methi, Judith Strauss, Ranjit Pradhan, Sophie Schröder, Susanne Burkhardt, Anna-Lena Schuetz, Tonatiuh Pena, Lena Erlebach, Anika Bühler, Monika Budde, Fanny Senner, Mojtaba Oraki Kohshour, Eva C Schulte, Max Schmauß, Eva Z Reininghaus, Georg Juckel, Deborah Kronenberg-Versteeg, Ivana Delalle, Francesca Odoardi, Alexander Flügel, Thomas G Schulze, Peter Falkai, Farahnaz Sananbenesi, Andre Fischer (2024)
Published 25. March 2024

EMBO J

https://doi.org/10.1038/s44318-024-00067-8

Publication

Gender-Specific Effects on the Cardiorespiratory System and Neurotoxicity of Intermittent and Permanent Low-Level Lead Exposures

Liana Shvachiy, Angela Amaro.Leal, Filipa Machado, Isabel Rocha,Tiago F. Outeiro, Vera Geraldes (2024)
Published 22. March 2024

BioMed

http://dx.doi.org/10.3390/biomedicines12040711

Publication

NanoPlex: a universal strategy for fluorescence microscopy multiplexing using nanobodies with erasable signals

Nikolaos Mougios, Elena R. Cotroneo, Nils Imse, Jonas Setzke, Silvio Rizzoli, Nadja A. Simeth, Roman Tsukanov, Felipe Opazo (2024)
Published 20. March 2024

BioRxiv

https://doi.org/10.1101/2024.03.18.585511

Publication

Synphilin-1 as a modulator of aSyn assembly

Diana F. Lázaro, Triana Amen, Ellen Gerhardt, Patrícia I. Santos, Dragomir Milovanovic, Günter Höglinger, Tiago F. Outeiro (2024)
Published 8. March 2024

BioRxiv

http://dx.doi.org/10.1101/2024.03.05.583522

Publication

Inhibition of 26S proteasome activity by α-synuclein is mediated by the proteasomal chaperone Rpn14/PAAF1

Dajana Galka, Tariq T. Ali, Alexander Bast, Marie Niederleithinger, Ellen Gerhardt, Ryo Motosugi, Eri Sakata, Michael Knop, Tiago F. Outeiro, Blagovesta Popova, Gerhard H. Braus (2024)
Published 28. February 2024

Aging Cell

http://dx.doi.org/10.1111/acel.14128

Publication

Near-optimal information relay by the neuronal population of layer 4 barrel cortex

Omer Revah, Fred Wolf, Michael J. Gutnick, Andreas Neef (2024)
Published 16. February 2024

BioRxiv

https://doi.org/10.1101/2024.02.15.580451

Publication

Subcellular Protein Turnover in Human Neural Progenitor Cells Revealed by Correlative Electron Microscopy and Nanoscale Secondary Ion Mass Spectrometry Imaging

Alicia A. Lork, Stefania Rabasco, Carl Ernst, André du Toit, Silvio O. Rizzoli, Nhu T. N. Phan (2024)
Published 29. January 2024

Chem Sci

http://dx.doi.org/10.1039/d3sc05629e

Publication

Vesicle condensation induced by synapsin: condensate size, geometry, and vesicle shape deformations

Jette Alfken, Charlotte Neuhaus, Andras Major, Alyona Taskina, Christian Hoffmann, Marcelo Ganzella, Arsen Petrovic, David Zwicker, Ruben Fernandez-Busnadiego, Reinhard Jahn, Dragomir Milovanovic, Tim Salditt (2024).
Published 25. January 2024

Springer

https://doi.org/10.1140/epje/s10189-023-00404-5

Publication

Advancing cell biology with nanoscale fluorescence imaging: essential practical considerations

Elisa DʼEste, Gražvydas Lukinavičius, Richard Lincoln, Felipe Opazo, Eugenio F. Fornasiero (2024)
Published 5. January 2024

Trends Cell Biol

https://doi.org/10.1016/j.tcb.2023.12.001

Publication

Substitution of Met-38 to Ile in γ-synuclein found in two patients with amyotrophic lateral sclerosis induces aggregation into amyloid

Liam D. Aubrey, Natalia Ninkina, Sabine M. Ulamec, Natalia Y. Abramycheva, Eftychia Vasili, Oliver M. Devine, Martin Wilkinson, Eilish Mackinnon, Galina Limorenko, Martin Walko, Sarah Muwanga, Leonardo Amadio, Owen M. Peters, Sergey N. Illarioshkin, Tiago F. Outeiro, Neil A. Ranson, David J. Brockwell, Vladimir L. Buchman, Sheena E. Radford (2024)
Published 3. January 2024

PNAS

https://doi.org/10.1073/pnas.2309700120

Publication

2024

Region-Specific Phosphorylation Determines Neuroligin-3 Localization to Excitatory Versus Inhibitory Synapses

Bekir Altas, Liam P. Tuffy, Annarita Patrizi, Kalina Dimova, Tolga Soykan, Cheryl Brandenburg, Andrea J. Romanowski, Julia R. Whitten, Colin D. Robertson, Saovleak N. Khim, Garrett W. Crutcher, Mateusz C. Ambrozkiewicz, Oleksandr Yagensky, Dilja Krueger-Burg, Matthieu Hammer, He-Hsuan Hsiao, Pawel R. Laskowski, Lydia Dyck, Adam C. Puche, Marco Sassoè-Pognetto, John J.E. Chua, Henning Urlaub, Olaf Jahn, Nils Brose, Alexandros Poulopoulos (2023)
Published 27. December 2023

Sci Dir

http://dx.doi.org/10.1016/j.biopsych.2023.12.020

Publication

Developmental changes of the mitochondria in the murine anteroventral cochlear nucleus

Anika Hintze, Felix, Lange, Anna M. Steyer, Jannis Anstatt, Wiebke Möbius, Stefan Jakobs, Carolin Wichmann (2023)
Published 8. December 2023

iSci

https://doi.org/10.1016/j.isci.2023.108700

Publication

Lipid vesicle pools studied by passive X-ray microrheology

Titus Czajka, Charlotte Neuhaus, Jette Alfken, Moritz Stammer, Yuriy Chushkin, Diego Pontoni, Christian Hoffmann, Dragomir Milovanovic, Tim Salditt (2023)
Published 7. December 2023

Springer

https://doi.org/10.1140/epje/s10189-023-00375-7

Publication

Excess phosphoserine-129 α-synuclein induces synaptic vesicle trafficking and declustering defects at a vertebrate synapse

Jaqulin N. Wallace, Zachary C. Crockford, Cristina Román-Vendrell, Emily B. Brady, Christian Hoffmann, Karina J. Vargas, Mariana Potcoava, M. Elizabeth Wegman, Simon T. Alford, Dragomir Milovanovic, Jennifer R. Morgan (2023)
Published 22. November 2023

MBoc

http://dx.doi.org/10.1091/mbc.e23-07-0269

Publication

Prediction mismatch responses arise as corrections of a predictive spiking code

Kjartan van Driel, Lucas Rudelt, Viola Priesemann, Fabian A. Mikulasch (2023)
Published 17. November 2023

BioRxiv

https://doi.org/10.1101/2023.11.16.567335

Publication

ATG9 resides on a unique population of small vesicles in presynaptic nerve terminals.

Beyenech Binotti, Momchil Ninov, Andreia P. Cepeda, Marcelo Ganzella, Ulf Matti, Dietmar Riedel, Henning Urlaub, Sivakumar Sambandan, Reinhard Jahn (2023)
Published 8. November 2023

Autoph

http://dx.doi.org/10.1080/15548627.2023.2274204

Publication

FAT10 is phosphorylated by IKKβ to inhibit the antiviral type-I interferon response.

Kritika Saxena, Nicola Domenico Roverato, Melody Reithmann, Mei Min Mah, Richard Schregle, Gunter Schmidtke, Ivan Silbern, Henning Urlaub, Annette Aichem (2023)
Published 8. November 2023

Life Sci All

http://dx.doi.org/10.26508/lsa.202101282

Publication

Mammalian oocytes store proteins for the early embryo on cytoplasmic lattices.

Ida M.A. Jentoft, Felix J.B. Bäuerlein, Luisa M. Welp, Benjamin H. Cooper, Arsen Petrovic, Chun So, Sarah Mae Penir, Antonio Z. Politi, Yehor Horokhovskyi, Iina Takala, Heike Eckel, Rüdiger Moltrecht, Peter Lénárt, Tommaso Cavazza, Juliane Liepe, Nils Brose, Henning Urlaub, Rubén Fernández-Busnadiego, Melina Schuh (2023)
Published 2. November 2023

Cell

http://dx.doi.org/10.1016/j.cell.2023.10.003

Publication

Tunable synaptic working memory with volatile memristive devices

Saverio Ricci, David Kappel, Christian Tetzlaff, Daniele Ielmini, Erika Covi (2023)
Published 31. October 2023

IOP  Sci

https://doi.org/10.1088/2634-4386/ad01d6

Publication

Synapsin condensation controls synaptic vesicle sequestering and dynamics

Christian Hoffmann, Jakob Rentsch, Taka A. Tsunoyama, Akshita Chhabra, Gerard Aguilar Perez, Rajdeep Chowdhury Franziska Trnka, Aleksandr A. Korobeinikov, Ali H. Shaib, Marcelo Ganzella, Gregory Giannone, Silvio O. Rizzoli, Akihiro Kusumi, Helge Ewers, Dragomir Milovanovic (2023)
Published 23. October 2023

Nat Comm

http://dx.doi.org/10.1038/s41467-023-42372-6

Publication

Neuronal activity modulates the incorporation of newly translated PSD-95 into a robust structure as revealed by STED and MINFLUX

Clara-Marie Gürth, Maria Augusta do Rego Barros Fernandes Lima, Victor Macarrón Palacios, Jasmine Hubrich, Angel Rafael Cereceda Delgado, Nikolaos Mougios, Opazo, Elisa D’Este (2023)
Published 20. October 2023

bioRxiv

https://doi.org/10.1101/2023.10.18.562700

Publication

PrP meets alpha-synuclein: Molecular mechanisms and implications for disease

Tuane C. R. G. Vieira, Caroline A. Barros, Renato Domingues, Tiago Fleming Outeiro (2023)

Published 19. October 2023

J Neurochem

http://dx.doi.org/10.1111/jnc.15992

Publication

High-resolution analysis of bound Ca2+ in neurons and synapses

Elisa A. Bonnin, Arash Golmohammadi, Ronja Rehm, Christian Tetzlaff, Silvio O. Rizzoli (2023)

Published 13. October 2023

Life Science

http://doi.org/10.26508/lsa.202302030

Publication

Phosphatases modified by LH signaling in ovarian follicles: testing their role in regulating the NPR2 guanylyl cyclase

Jeremy R Egbert, Ivan Silbern, Tracy F Uliasz, Katie M Lowther, Siu-Pok Yee, Henning Urlaub, Laurinda A Jaffe (2023)
Published 29. September 2023
BioRep

http://dx.doi.org/10.1093/biolre/ioad130

Publication

Fibroblast growth factor 9 (FGF9)-mediated neurodegeneration: Implications for progressive multiple sclerosis?

Katja Thümmler, Claudia Wrzos, Jonas Franz, Daniel McElroy, John J. Cole, Lorna Hayden, Diana Arseni, Friedrich Schwarz, Andreas Junker, Julia M. Edgar, Sebastian Kügler, Andreas Neef, Fred Wolf, Christine Stadelmann, Christopher Linington (2023)
Published 13. September 2023
Neuropath All Neurobiol

https://dx.doi.org/10.1111/nan.12935

Publication

Control of intracellular pH and bicarbonate by CO2 diffusion into human sperm

Elena Grahn, Svenja V. Kaufmann, Malika Askarova, Momchil Ninov, Luisa M. Welp, Thomas K. Berger, Henning Urlaub, U. Benjamin Kaupp (2023)
Published 5. September 2023

Nat Comm

http://dx.doi.org/10.1038/s41467-023-40855-0

Publication

Increased alpha-synuclein and neuroinflammation in the substantia nigra triggered by systemic inflammation are reversed by targeted inhibition of the receptor for advanced glycation end products (RAGE).

Daniel Oppermann Peixoto, Reykla Ramon Bittencourt, Juciano Gasparotto, Flávio Gabriel Carazza Kessler, Pedro Ozorio Brum, Nauana Somensi, Carolina Saibro Girardi, Lucas dos Santos da Silva, Tiago F. Outeiro, José Cláudio Fonseca Moreira, Daniel Pens Gelain (2023)
Published 3. September 2023

J Neurochem

https://onlinelibrary.wiley.com/doi/abs/10.1111/jnc.15956

Publication

Changes in α-Synuclein Posttranslational Modifications in an AAV-Based Mouse Model of Parkinson’s Disease

Viviana Brembati, Gaia Faustini, Francesca Longhena, Tiago F. Outeiro, Arianna Bellucci (2023)
Published 30. August 2023

Int J Mol Sci

http://dx.doi.org/10.3390/ijms241713435

Publication

The alpha-synuclein oligomers activate nuclear factor of activated T-cell (NFAT) modulating synaptic homeostasis and apoptosis

Ricardo Sant’Anna, Bruno K. Robbs, Julia Araujo de Freitas, Patricia Pires dos Santos, Annekatrin König, Tiago F. Outeiro, Debora Foguel (2023)
Published 18. August 2023

Mol Med

http://dx.doi.org/10.1186/s10020-023-00704-8

Publication

A viral ADP-ribosyltransferase attaches RNA chains to host proteins

Maik Wolfram-Schauerte, Nadiia Pozhydaieva, Julia Grawenhoff, Luisa M. Welp, Ivan Silbern, Alexaner Wulf, Franziska A. Billau, Timo Glatter, Henning Urlaub, Andres Jäschke, Katharina Höfer (2023)
Published 16. August 2023

Nat

http://dx.doi.org/10.1038/s41586-023-06429-2

Publication

Age-dependent structural reorganization of utricular ribbon synapses

Susann Michanski, Timo Henneck, Mohona Mukhopadhyay, Anna M. Steyer, Paola Agüi Gonzalez, Katharina Grewe, Peter Ilgen, Mehmet Gültas, Eugeno F. Fornasiero, Stefan Jakobs, Wiebke Möbius, Christian Vogl, Tina Pangrsic, Silvio O. Rizzoli, Carolin Wichmann (2023)
Published 10. August 2023

Front Cell

https://doi.org/10.3389/fcell.2023.1178992

Publication

Uncovering the Molecular Link Between Lead Toxicity and Parkinson's Disease

Liana Shvachiy, Vera Geraldes, Tiago F. Outeiro (2023)
Published 9. August 2023

Antioxid RS

http://dx.doi.org/10.1089/ars.2022.0076

Publication

Metabolic switch from fatty acid oxidation to glycolysis in knock‐in mouse model of Barth syndrome

Arpita Chowdhury, Angela Boshnakovska, Abhishek Aich, Aditi Methi, Ana Maria Vergel Leon, Ivan Silbern, Christian Lüchtenborg, Lukas Cyganek, Jan Prochazka, Radislav Sedlacek, Jiri Lindovsky, Dominic Wachs, Zuzana Nichtova, Dagmar Zudova, Gizela Koubkova, André Fischer, Henning Urlaub, Britta Brügger, Dörthe M Katschinski, Jan Dudek, Peter Rehling (2023)
Published 3. August 2023

EMBO

https://www.embopress.org/doi/full/10.15252/emmm.202317399

Publication

Aggregation and beyond: alpha-synuclein-based biomarkers in synucleinopathies

Avika Chopra, Tiago F. Outeiro (2023)
Published 1. August 2023

Brain

http://dx.doi.org/10.1093/brain/awad260

Publication

Proteomic analysis of the human hippocampus identifies neuronal pentraxin 1 (NPTX1) as synapto-axonal target in late-stage Parkinson's disease

Carmina C. Warth Perez Arias, Ivan Silbern, Lucas Caldi Gomes, Hannes Wartmann, Vivian Dambeck, Jonas Fanz, Lisa Neuenroth, Mathias Bähr, Tiago F. Outeiro, Stefan Bonn, Christine Stadelmann-Nessler, Silvio O. Rizzoli, Christof Lenz, Henning Urlaub, Paul (2023)
Published 28. July 2023

J Neurochem

http://dx.doi.org/10.1111/jnc.15924

Publication

An intellectual-disability-associated mutation of the transcriptional regulator NACC1 impairs glutamatergic neurotransmission

James A. Daniel, Sofia Elizarova, Ali H. Shaib, Abed A. Chouaib, Helge M. Magnussen, Jianlong Wang, Nils Brose, JeongSeop Rhee, Marilyn Tirard (2023)
Published 14. July 2023

Front Mol

https://doi.org/10.3389/fnmol.2023.1115880

Publication

A Versatile Synaptotagmin-1 Nanobody Provides Perturbation-Free Live Synaptic Imaging And Low Linkage-Error in Super-Resolution Microscopy

Karine Queiroz Zetune Villa Real, Nikolaos Mougios, Ronja Rehm, Shama Sograte-Idrissi, László Albert, Amir Mohammad Rahimi, Manuel Maidorn, Jannik Hentze, Markel Martínez-Carranza, Hassan Hosseini, Kim-Ann Saal, Nazar Oleksiievets, Matthias Prigge, Roman Tsukanov, Pål Stenmark, Eugenio F. Fornasiero, Felipe Opazo (2023)

Published 8. July 2023

Small methods

https://doi.org/10.1002/smtd.202300218

Publication

AI and protein structure and function in neurological disease: relevance to disease management

Tiago F. Outeiro, Tuane C.R.G. Vieira (2023)

Published 2. July 2023

Nat Rev Neurol

http://dx.doi.org/10.1038/s41582-023-00840-z

Publication

Is it all the RAGE? Defining the role of the receptor for advanced glycation end products in Parkinson's disease

Juciano Gasparotto, Nauana Somensi, Carolina Saibro Girardi, Reykla Ramon Bittencourt, Laura Martinewski de Oliveira, Laura Piloneto Hoefel, Ingrid Matsubara Scheibel, Daniel Oppermann Peixoto, José Claudio Fonseca Moreira, Tiago Fleming Outeiro, Daniel Pens Gelain (2023)

Published 28. June 2023

J Neurochem

http://dx.doi.org/10.1111/jnc.15890

Publication

Boosting of neural circuit chaos at the onset of collective oscillations

Agostina Palmigiano, Rainer Engelken, Fred Wolf (2023)

Published 21. June 2023

eLife

http://dx.doi.org/10.1101/2022.08.28.505598

Publication

Polychaetoid/ZO-1 strengthens cell junctions under tension while localizing differently than core adherens junction proteins

Anja Schmidt, Tara Finegan, Matthias Häring, Deqing Kong, Alexander G Fletcher, Zuhayr Alam, Jörg Grosshans, Fred Wolf, Mark Pfeifer (2023)

Published 20. June 2023

MBoC

http://dx.doi.org/10.1091/mbc.e23-03-0077

Publication

Mechanisms of simultaneous linear and nonlinear computations at the mammalian cone photoreceptor synapse

Chad Grabner, Daiki Futagi, Jun Shi, Vytas Bindokas, Katsunori Kitano, Eric Schwartz, Steven deVries (2023)

Published 16. June 2023

Nat Comm
http://dx.doi.org/10.1038/s41467-023-38943-2

corrected 20. March 2024, Nat Comm
http://dx.doi.org/10.1038/s41467-024-45588-2

Publication

The long-loop recycling (LLR) of synaptic components as a question of economics

Svilen Georgiev, Silvio O. Rizzoli (2023)

Published 24. May 2023

SciDi

https://doi.org/10.1016/j.mcn.2023.103862

Publication

Spatial proteomics in neurons at single-protein resolution

Eduard M. Unterauer, Sayedali Shetab Boushehri, Kristina Jevdokimenko, Luciano A. Masullo, Mahipal Ganji, Shama Sograte-Idrissi, Rafal Kowalewski, Sebastian Strauss, Susanne C.M. Reinhardt, Ana Perovic, Carsten Marr, Felipe Opazo, Eugenio F. Fornasiero, Ralf Jungmann (2023)

Published 18. May 2023

Bio Rxiv

https://doi.org/10.1101/2023.05.17.541210

Publication

Expansion-enhanced super-resolution radial fluctuations enable nanoscale molecular profiling of pathology specimens.

Dominik Kylies, Marina Zimmermann, Fabian Haas, Maria Schwerk, Malte Kuehl, Michael Brehler, Jan Czogalla, Lola C. Hernandez, Leonie Konczall, Yusuke Okabayashi, Julia Menzel, Ilka Edenhofer, Sam Mezher, Hande Aypek, Bernhard Dumoulin, Hui Wu, Smilla Hofmann, Oliver Kretz, Nicola Wanner, Nicola M. Tomas, Susanne Krasemann, Markus Glatzel, Christoph Kuppe, Rafael Kramann, Bella Banjanin, Rebekka K. Schneider, Christopher Urbschat, Petra Arck, Nicola Gagliani, Marc van Zandvoort, Thorsten Wiech, Florian Grahammer, Pablo J. Sáez, Milagros N. Wong, Stefan Bonn, Tobias B. Huber, Victor G. Puelles (2023)

Published 10. April 2023

Nat Nanotechnol

http://dx.doi.org/10.1038/s41565-023-01328-z

Publication

Towards a Biological Definition of Parkinson’s Disease

Günter U. Höglinger, Charles H. Adler, Daniela Berg, Christine Klein, Tiago F. Outeiro, Werner Poewe, Ronald Postuma, Jon Stoessl, Anthony E. Lang (2023)

Published 7. April 2023

Preprints

http://dx.doi.org/10.20944/preprints202304.0108.v1

Publication

Reverse-time analysis uncovers universality classes in directional biological dynamics

Nicolas Lenner, Stephan Eule, Jörg Großhans, Fred Wolf (2023)

Published 6. April 2023

arXiv

https://arxiv.org/abs/2304.03226

Publication

Chemical Synthesis of Alpha-Synuclein Proteins via Solid-Phase Peptide Synthesis and Native Chemical Ligation

Luisa Maria Gatzemeier, Prof. Dr. Franc Meyer, Prof. Dr. Ulf Diederichsen, Prof. Dr. Tiago Fleming Outeiro (2023)

Published 27. March 2023

Chem Euro J

http://dx.doi.org/10.1002/chem.202300649

Publication

Neurofilament Levels in Dendritic Spines Associate with Synaptic Status

Clara-Marie Gürth, Maira Augusta do Rego Barros Fernandes Lima, Victor Macarrón Palacios, Angel Rafael Cereceda Delgado, Jasmine Hubrich, Elisa D’Este (2023)

Published 15. March 2023

Cells

https://doi.org/10.3390/cells12060909

Publication

Characterizing the differential distribution and targets of Sumo1 and Sumo2 in the mouse brain

Terry R. Suk, Trina T. Nguyen, Zoe A. Fisk, Miso Mitkovski, Haley M. Geertsma, Jean-Louis A. Parmasad, Meghan M. Heer, Steve M. Callaghan, Fritz Benseler, Nils Brose, Marilyn Tirard, Maxime W.C. Rousseaux (2023)

Published 9. March 2023

ISci

https://doi.org/10.1016/j.isci.2023.106350

Publication

Intermittent Lead Exposure Induces Behavioral and Cardiovascular Alterations Associated with Neuroinflammation

Liana Shvachiy, Angela Amaro-Leal, Tiago F. Outeiro, Isabel Rocha, Vera Geradles (2023)
Published  6. March 2023

Cells

http://dx.doi.org/10.3390/cells12050818

Publication

The multifaceted mitochondrial OXA insertase

Bettina Homberg, Peter Rehling, Luis Daniel Cruz-Zaragoza (2023)
Published  28. February 2023

Cell Bio

http://dx.doi.org/10.1016/j.tcb.2023.02.001

Publication

Alpha-synuclein oligomers activate NFAT proteins modulating synaptic homeostasis and apoptosis.

Ricardo Sant’Anna, Bruno K Robbs, Júlia Araújo de Freitas, Patrícia Pires dos Santos, Annekatrin König, Tiago F. Outeiro, Debora Foguel (2023)
Published  24. February 2023

BioRxiv

http://dx.doi.org/10.1101/2023.02.21.529374

Publication

Neuronal extracellular vesicles and associated microRNAs induce circuit connectivity downstream BDNF

Anna Antoniou, Loic Auderset, Lalit Kaurani, Eva Sebastian, Yuzhou Zeng, Maria Allahham, Silvia Cases-Cunillera, Susanne Schoch, Jan Gründemann, Andre Fischer, Anja Schneider (2023)
Published 6. February 2023

Cell Rep

https://doi.org/10.1016/j.celrep.2023.112063

Publication

A versatile synaptotagmin-1 nanobody provides perturbation-free live synaptic imaging and low linkage-error in super-resolution microscopy

Karine Queiroz Zetune Villa Real, Nikolaos Mougios, Ronja Rehm, Shama Sograte-Idrissi, László Albert, Amir Mohammad Rahimi, Manuel Maidorn, Jannik Hentze, Markel Martínez-Carranza, Hassan Hosseini, Kim-Ann Saal, Nazar Oleksiievets, Matthias Prigge, Roman Tsukanov, Pål Stenmark, Eugenio F. Fornasiero, Felipe Opazo (2023)
Published 1. February 2023

BioRxiv

https://www.biorxiv.org/content/10.1101/2023.01.30.525828v2

Publication

Condensate biology of synaptic vesicle clusters

Roberto Sansevrino, Christian Hoffmann, Dragomir Milovanovic (2023)
Published 30. January 2023

Trend Neurosci

http://dx.doi.org/10.1016/j.tins.2023.01.001

Publication

Deep learning enables fast, gentle STED microscopy

Vahid Ebrahimi, Till Stephan, Jiah Kim, Pablo Carravilla, Christian Eggeling, Stefan Jakobs, Kyu Young Han (2023)
Published 27. January 2023

BioRxiv
http://dx.doi.org/10.1101/2023.01.26.525571

http://dx.doi.org/10.1038/s42003-023-05054-z
Now published 27. June 2023 Comm Bio

Publication

Phase Separation in Biology and Disease; Current Perspectives and Open Questions

Steven Boeynaems, Shasha Chong, Jörg Gsponer, Liam Holt, Dragomir Milovanovic, Diana M. Mitre, Oliver Mueller-Cajar, Bede Portz, John F. Reilly, Christopher D. Reinkemeier, Benjamin R. Sabari, Serena Sanulli, James Shorter, Emily Sontag, Lucia Strader, Jeanne Stachowiak, Stephanie C. Weber, Michael White, Huaiying Zhang, Markus Zweckstetter, Shana Elbaum-Garfinkle, Richard Kriwacki (2023)

Published 21. January 2023

J Mol Bio

http://dx.doi.org/10.1016/j.jmb.2023.167971

Publication

Neurodegenerative disease of the brain: a survey of interdisciplinary approaches

Franca Davenport, John Gallacher, Zoe Kourtzi, Ivan Koychev, Paul M. Matthews, Neil P. Oxtoby, Laura M. Parkes, Viola Priesemann, James B. Rowe, Stephen W. Smye, Henrik Zetterberg (2023)

Published 18. January 2023

J R Soc Interface

http://dx.doi.org/10.1098/rsif.2022.0406

Publication

Trafficking proteins show limited differences in mobility across different postsynaptic spines

Nikolaos Mougios, Felipe Opazo, Silvio O. Rizzoli Sofiia Reshetniak (2023)

Published 12. January 2023

ISci

https://doi.org/10.1016/j.isci.2023.105971

Publication

Age-dependent structural reorganization of utricular ribbon synapses

Susann Michanski, Timo Henneck, Mohona Mukhopadhyay, Anna M. Steyer, Paola Agüi Gonzalez, Katharina Grewe, Peter Ilgen, Mehmet Gültas, Eugeno F. Fornasiero, Stefan Jakobs, Wiebke Möbius, Christian Vogl, Tina Pangrsic, Silvio O. Rizzoli, Carolin Wichmann (2023)

Published 9. January 2023

BioRxiv
http://dx.doi.org/10.1101/2022.12.19.521049

now published 10. August 2023, Front
https://doi.org/10.3389/fcell.2023.1178992

Publication

2023

Stress - Regulation of SUMO conjugation and of other Ubiquitin‐Like Modifiers.

Dragana Ilic, Helge M. Magnussen, Marilyn Tirard (2022)
Published 23. December 2022

Sci Dir

https://doi.org/10.1016/j.semcdb.2021.12.010

Publication

ERR2 and ERR3 promote the development of gamma motor neuron functional properties required for proprioceptive movement control

Mudassar N. Khan, Pitchaiah Cherukuri, Francesco Negro, Ashish Rajput, Piotr Fabrowski, Vikas Bansal, Camille Lancelin, Tsung-I Lee, Yehan Bian, William P. Mayer, Turgay Akay, Daniel Müller, Stefan Bonn, Dario Farina, Till Marquardt (2022)

Published 21. December 2022

PLos Biol

http://dx.doi.org/10.1371/journal.pbio.3001923

Publication

Molecular Mechanisms Mediating the Transfer of Disease-Associated Proteins and Effects on Neuronal Activity

Inês C.a Brás, Mohammad Khani, Eftychiaa Vasili, Wiebke Möbius, Dietmar Riedel, Iwan Parfentev, Ellena Gerhardt, Christiane Fahlbusch, Henning Urlaub, Markus Zweckstetter, Tim Gollisch, Tiago Outeiro (2022).

Published 16. December 2022

J Parkinson Dis

http://dx.doi.org/10.3233/jpd-223516

Publication

Visuomotor Mismatch Responses as a Hallmark of Explaining Away in Causal Inference

Fabian A. Mikulasch, Lucas Rudelt, Viola Priesemann (2022)
Published 14. December 2022

Neuro Comp

https://doi.org/10.1162/neco_a_01546

Publication

Where is the error? Hierarchical predictive coding through dendritic error computation

Fabian A. Mikulasch, Lukas Rudelt, Michael Wibral, Viola Priesemann (2022)
Published 18. November 2022

Trends NeuroSci

https://doi.org/10.1016/j.tins.2022.09.007

Publication

Focused ion beam-scanning electron microscopy links pathological myelin outfoldings to axonal changes in mice lacking Plp1 or Mag

Anna M. Steyer, Tobias J. Buscham, Charlotta Lorenz, Sophie Hümmert, Maria A. Eichel-Vogel, Leonie C. Schadt, Julia M. Edgar, Sarah Köster, Wiebke Möbius, Klaus-Armin Nave, Hauke B. Werner (2022)
Published 10. November 2022

Glia

http://dx.doi.org/10.1002/glia.24290

Publication

Extracellular vesicles derived from the choroid plexus trigger the differentiation of neural stem cells

Zuzana Ditte, Ivan Silbern, Peter Ditte, Henning Urlaub, Gregor Eichele (2022).
Published 2. November 2022

J Extra Cell Ves

http://dx.doi.org/10.1002/jev2.12276

 

Publication

DiSCERN - Deep Single Cell Expression ReconstructioN for improved cell clustering and cell subtype and state detection

Fabian Hausmann, Can Ergen-Behr, Robin Khatri, Mohamed Marouf, Sonja Hänzelmann, Nicola Gagliani, Samuel Huber, Pierre Machart, Stefan Bonn (2022)
Published 20. September 2022

BioRxiv
http://dx.doi.org/10.1101/2022.03.09.483600

now published 20. September 2023, Gen Biol
https://doi.org/10.1186/s13059-023-03049-x

Publication

The future of Parkinson’s disease research: A new paradigm of human specific investigation is necessary… and possible.

Manuela Cassotta, Hugo Geerts, Lise Harbom, Tiago F. Outeiro, Iosif Pediaditakis, Orly Reiner, Stefan Schildknecht, Jens C. Schwamborn, Jarrod Bailey, Kathrin Herrmann, Helena T. Hogberg (2022)
Published 18. October 2022

Altex

http://dx.doi.org/10.14573/altex.2203161

Publication

Ectosomes and exosomes modulate neuronal spontaneous activity

Inês C. Brás, Mohammad H. Khani, Dietmar Riedel, Iwan Parfentev, Ellen Gerhardt, Christoph van Riesen, Henning Urlaub, Tim Gollisch, Tiago F. Outeiro (2022)
Published 8. September 2022

J Proteomics

http://dx.doi.org/10.1016/j.jprot.2022.104721

Publication

JM-20, a Benzodiazepine-Dihydropyridine Hybrid Molecule, Inhibits the Formation of Alpha-Synuclein-Aggregated Species

Cleonice Creusa Santos, Thyago R. Cardim‑Pires, Liana Shvachiy, Luis Arturo Fonseca‑Fonseca, Patricia Munoz, Aurea Maria A. N. Almeida, Ana Carla S. Costa, Jessica Teles‑Souza, Estael Ochoa‑Rodriguez, Maria de Fatima Dias Costa, Fernando L. Palhano, Juan Segura‑Aguilar, Deyse B. Barbosa, Mayra R. do Bomfim, Manoelito C. dos Santos Junior, Franco Henrique A. Leite, Samuel Silva da Rocha Pita, Silvia Lima Costa, Yanier Nunez‑Figueredo, Tiago F. Outeiro, Debora Foguel, Victor Diogenes Amaral Silva (2022)
Published 23. August 2022

NeuroTex Res

http://dx.doi.org/10.1007/s12640-022-00559-7

Publication

From Molecular to Functional Effects of Different Environmental Lead Exposure Paradigms

Liana Shvachiy, Angela Amaro-Leal, Tiago F. Outeiro, Isabel Rocha, Vera Geraldes (2022)
Published 3. August 2022

Bi Basel

http://dx.doi.org/10.3390/biology11081164

Publication

Resolving the molecular architecture of the photoreceptor active zone with 3D-MINFLUX

Chad Grabner, Jakob Neef, Tobias Weihs, Roman Schmidt, Dietmar Riedel, Christian A. Wurm, Tobias Moser (2022)
Published 15. July 2022

Sci Adv

http://dx.doi.org/10.1126/sciadv.abl7560

Publication

Nuclear alpha-synuclein is present in the human brain and is modified in dementia with Lewy bodies

David J. Koss, Daniel Erskine, Andrew Porter, Pawel Palmoski, Hariharan Menon, Olivia G. J. Todd, Marta Leite, Johannes Attems, Tiago F. Outeiro (2022)
Published 6. July 2022

Acta Neuropath Comm

http://dx.doi.org/10.1186/s40478-022-01403-x

Publication

Aromaticity at position 39 in α-synuclein: A modulator of amyloid fibril assembly and membrane-bound conformations

Fiamma A. Buratti, Nicola Boeffinger, Hugo A. Garro, Jesica S. Flores, Francisco J. Hita, Phelippe do Carmo Gonçalves, Federico dos Reis Copello, Leonardo Lizarraga, Giulia Rossetti, Paolo Carloni, Markus Zweckstetter, Tiago F. Outeiro, Stefan Eimer, Christian Griesinger, Claudio O. Fernández (2022)
Published 27. June 2022

Protein Sci

http://dx.doi.org/10.1002/pro.4360

Publication

Hsp multichaperone complex buffers pathologically modified Tau

Antonia Moll, Lisa Marie Ramirez, Momchil Ninov, Juliane Schwarz, Henning Urlaub, Markus Zweckstetter (2022)
Published 27. June 2022

Nat commun

https://doi.org/10.1038/s41467-022-31396-z

Publication

Conserved reduction of m6A marks during aging and neurodegeneration is linked to altered translation of synaptic transcripts

Ricardo Castro-Hernández, Tea Berulava, Maria Metelova, Robert Epple, Tonatiuh Peña Centeno, M Sadman Sakib, Susanne Burkhart, Momchil Ninov, Katherine E. Bohnsack, Markus T. Bohnsack, Ivana Delalle, Andre Fischer (2023)
Published 10. June 2022

BioRxiv
https://doi.org/10.1101/2022.06.08.495100

now published 22. February 2023, PNAS
https://doi.org/10.1073/pnas.2204933120

Publication

An Iodine-Containing Probe as a Tool for Molecular Detection in Secondary Ion Mass Spectrometry

Published 7. June 2022

Chem Comm

https://doi.org/10.1039/D2CC02290G

Publication

Alpha-synuclein overexpression induces epigenomic dysregulation of glutamate signaling and locomotor pathways

http://dx.doi.org/10.1093/hmg/ddac104

Samantha L Schaffner, Zinah Wassouf, Diana F Lazaro, Mary Xylaki, Nicole Gladish, David T S Lin, ulia MacIsaac, Katia Ramadori, Thomas Hentrich, Julia M Schulze-Hentrich, Tiago F Outeiro, Michael S Kobor (2022)

Published 14. May 2022

Hum Mol Genet

http://dx.doi.org/10.1093/hmg/ddac104

Publication

Optogenetics and electron tomography for structure-function analysis of cochlear ribbon synapses.

Rituparna Chakrabarti, Lina María Jaime Tobón, Loujin Slitin, Magdalena Redondo Canales, Gerhard Hoch, Marina Slashcheva, Elisabeth Fritsch, Kai Bodensiek, Özge Demet Özçete, Mehmet Gültas, Susann Michanski, Felipe Opazo, Jakob Neef, Tina Pangrsic, Tobias Moser, Carolin Wichmann
 (2022)
Published 10. May 2022

BioRixv
https://www.biorxiv.org/content/10.1101/2022.05.10.491334

now published 23. December 2022, eLife
https://doi.org/10.7554/eLife.79494

Publication

α-Synuclein Impacts on Intrinsic Neuronal Network Activity Through Reduced Levels of Cyclic AMP and Diminished Numbers of Active Presynaptic Terminals

Kristian Leite, Pretty Garg, F. Paul Spitzner, Sofia Guerin Darvas, Mathias Bär, Viola Priesemann, Sebastian Kügler (2022)
Published 3. May 2022

Front Mol NeuroSci

https://doi.org/10.3389/fnmol.2022.868790

Publication

Glycation modulates glutamatergic signaling and exacerbates Parkinson’s disease-like phenotypes

Ana Chegão, Mariana Guarda, Bruno M. Alexandre, Liana Shvachiy, Mariana Temido-Ferreira, Inês Marques-Morgado, Bárbara Fernandes Gomes, Rune Matthiesen, Luísa V. Lopes, Pedro R. Florindo, Ricardo A. Gomes, Patrícia Gomes-Alves, Joana E. Coelho, Tiago F Outeiro, Hugo Vicente Miranda (2022)
Published 25. April 2022

npj Parkinson Dis

http://dx.doi.org/10.1038/s41531-022-00314-x

Publication

The small aromatic compound SynuClean-D inhibits the aggregation and seeded polymerization of multiple α-synuclein strains

Samuel Peña-Díaz, Jordi Pujols, Eftychia Vasili, Francisca Pinheiro, Jaime Santos, Zoe Manglano-Artuñedo, Tiago F. Outeiro, Salvador Ventura (2022)
Published 4. April 2022

J Biol Chem

http://dx.doi.org/10.1016/j.jbc.2022.101902

Publication

ECM recycling as a novel plasticity mechanism with a potential role in disease

Tal Dankovich, Silvio O. Rizzoli (2022)
Published 31. March 2022

Front Cell Neurosci

https://doi.org/10.3389/fncel.2022.854897

Publication

Extracellular alpha-synuclein: Sensors, receptors, and responses.

Renato Domingues, Ricardo Sant’Anna, Anna Carolina Carvalho da Fonseca, Bruno K. Robbs, Debora Foguel, Tiago F. Outeiro (2022)
Published 20. March 2022

Neurobiol Dis

http://dx.doi.org/10.1016/j.nbd.2022.105696

Publication

Methods for multiscale structural and functional analysis of the mammalian cochlea

Christian Vogl, Jakob Neef, Carolin Wichmann (2022)
Published 11. March 2022

Sci Dir

http://dx.doi.org/10.1016/j.mcn.2022.103720

Publication

Colocalization of different neurotransmitter transporters on synaptic vesicles is sparse except for VGLUT1 and ZnT3

Neha Upmanyu, Jialin Jin, Henrik von der Emde, Marcelo Ganzella, Leon Bösche, Viveka Nand Malviya, Evi Zhuleku, Antonio Zaccaria Politi, Momchil Ninov, Ivan Silbern, Marcel Leutenegger, Henning Urlaub, Dietmar Riedel, Julia Preobraschenski, Ira Milosevic, Stefan W.Hell, Reinhard Jahn, Sivakumar Sambandan (2022)
Published 8. March 2022

Neuron

https://doi.org/10.1016/j.neuron.2022.02.008

Publication

The synaptic extracellular matrix: long-lived, stable, and still remarkably dynamic

Tal Dankovich, Silvio O. Rizzoli (2022)
Published 8. March 2022

Front Syn Neuro

https://doi.org/10.3389/fnsyn.2022.854956

Publication

White Matter Integrity Requires Continuous Myelin Synthesis at The Inner Tongue in Mice

Martin Meschkat, Anna M. Steyer, Marie-Theres Weil, Kathrin Kusch, Olaf Jahn, Lars Piepkorn, Paola Agüi-Gonzalez, Nhu Thi Ngoc Phan, Torben Ruhwedel, Boguslawa Sadowski, Silvio O. Rizzoli, Hauke B. Werner, Hannelore Ehrenreich, Klaus-Armin Nave, Wiebke Möbius (2022)
Published 4. March 2022

Nat commun

https://doi.org/10.1038/s41467-022-28720-y

Publication

Identification of distinct cytotoxic granules as the origin of supramolecular attack particles in T lymphocytes

Hsin-Fang Chang, Claudia Schirra, Momchil Ninov, Ulrike Hahn, Keerthana Ravichandran, Elmar Krause, Ute Becherer, Štefan Bálint, Maria Harkiolaki, Henning Urlaub, Salvatore Valitutti, Cosima T Baldari, Michael L Dustin, Reinhard Jahn, Jens Rettig (2022)
Published 24. February 2022

Nat comm

https://doi.org/10.1038/s41467-022-28596-y

Publication

Environmental enrichment enhances patterning and remodeling of synaptic nanoarchitecture as revealed by STED nanoscopy

Waja Wegner, Heinz Steffens, Carola Gregor, Fred Wolf, Katrin I Willig (2022)
Published 23. February 2022

eLife

https://doi.org/10.7554/eLife.73603

Publication

Monitoring the interactions between alpha-synuclein and Tau in vitro and in vivo using bimolecular fluorescence complementation

Laura Torres-Garcia, Joana M.P. Domingues, Edoardo Brandi, Caroline Haikal, Janitha M. Mudannayake, Ines C. Bras, Ellen Gerhardt, Wen Li, Alexander Svanbersson, Tiago F. Outeiro, Gunnar K. Gouras (2022)
Published 22. February 2022

Sci Rep

http://dx.doi.org/10.1038/s41598-022-06846-9

Publication

Ultrafast population coding and axo-somatic compartmentalization

Chenfei Zhang, David Hofmann, Andreas Neef, Fred Wolf (2022)
Published 18. January 2022

PLOS

https://doi.org/10.1371/journal.pcbi.1009775

Publication

Signals from the interface: protein nanoclusters stabilize biomolecular condensates.

Christian Hoffmann, Branislava Rankovic, Dragomir Milovanovic (2022
Published 13. January 2022

Signal Trans TT

http://dx.doi.org/10.1038/s41392-022-00876-5

Publication

Co-localization of different neurotransmitter transporters on synaptic vesicles is sparse except of VGLUT1 and ZnT3

Neha Upmanyu, Jialin Jin, Henrik von der Emde, Marcelo Ganzella, Leon Bösche, Viveka Nand Malviya, Evi Zhuleku, Antonio Politi, Momchil Ninov, Ivan Silbern, Marcel Leutenegger, Henning Urlaub, Dietmar Riedel, Julia Preobraschenski, Ira Milosevic, Stefan W Hell, Reinhard Jahn, Sivakumar Sambandan (2022)
Published 10. January 2022

BioRxiv

http://dx.doi.org/10.1101/2021.06.30.449903

Publication

Prion-like α-synuclein pathology in the brain of infants with Krabbe disease

Christopher Hatton, Simona S. Ghanem, David J. Koss, Ilham Y. Abdi, Elizabeth Gibbons, Rita Guerreiro, Jose Bras, International DLB Genetics Consortium, Lauren Walker, Ellen Gelpi, Wendy Heywood, Tiago F. Outeiro, Johannes Attems, Robert McFarland, Rob Forsyth, Omar M. El-Agnaf, Daniel Erskine (2022)
Published 6. January 2022

Brain

http://dx.doi.org/10.1093/brain/awac002

Publication

Endogenous Levels of Alpha-Synuclein Modulate Seeding and Aggregation in Cultured Cells

Eftychia Vasili, Antonio Dominguez-Meijide, Manuel Flores-León, Mohammed Al-Azzani, Angeliki Kanellidi, Ronald Melki, Leonidas Stefanis, Tiago Fleming Outeiro (2022)
Published 4. January 2022

Mol Neurobiol

http://dx.doi.org/10.1007/s12035-021-02713-2

Publication

2022

Extracellular matrix remodeling through endocytosis and resurfacing of Tenascin-R

Tal M. Dankovich, Rahul Kaushik, Linda HM Olsthoorn, Gabriel Cassinelli Petersen, Philipp Emanuel Giro, Verena Klüver, Paola Agüi-Gonzalez, Katharina Grewe, Guobin Bao, Sabine Beuermann, Hannah Abdul Hadi, Jose Dören, Simon Klöppner, Benjamin H. Cooper, Alexander Dityatev, Silvio O. Rizzoli (2021)
Published 8. December 2021

Pub Med

https://doi.org/10.1038/s41467-021-27462-7

Publication

Nuclear alpha-synuclein is present in the human brain and is modified in dementia with Lewy bodies

David J. Koss, Daniel Erskine, Andrew Porter, Pawel Palmoski, Marta Leite, Johannes Attems, Tiago F. Outeiro (2021)

Published 7. December 2021

BioRxiv

http://dx.doi.org/10.1101/2021.10.20.465125

Publication

Punctuated evolution of visual cortical circuits? Evidence from the large rodent Dasyprocta leporina, and the tiny primate Microcebus murinus

Kerstin E. Schmidt, Fred Wolf (2021)

Published 22. November 2021

Sci Dir

http://dx.doi.org/10.1016/j.conb.2021.10.007

Publication

Postnatal expression of the lysine methyltransferase SETD1B is essential for learning and the regulation of neuron-enriched genes

Alexandra Michurina, M. Sadman Sakib, Cemil Kerimoglu, Dennis Manfred Krüger, Lalit Kaurani, Md Rezaul Islam, Parth Devesh Joshi, Sophie Schröder, Tonatiuh Pena Centeno, Jiayin Zhou, Ranjiit Pradhan, Julia Cha, Xingbo Xu, Gregor Eichele, Elisabeth M. Zeisberg, Andrea Kranz, A. Francis Stewart, Andre Fischer (2021).

Published 22. November 2021

EMBO J

https://doi.org/10.15252/embj.2020106459

Publication

Three-dimensional virtual histology of the cerebral cortex based on phase-contrast X-ray tomography

Marina Eckermann, Franziska van der Meer, Peter Cloetens, Torben Ruhwedel, Wiebke Möbius, Christine Stadelmann,Tim Salditt (2021)
Published 15. November 2021

OPG

http://dx.doi.org/10.1364/boe.434885

Publication

Interferon-driven brain phenotype in a mouse model of RNaseT2 deficient leukoencephalopathy

Matthias Kettwig, Katharina Ternka, Kristin Wendland, Dennis Manfred Krüger, Silvia Zampar, Charlotte Schob, Jonas Franz, Abhishek Aich, Anne Winkler, M. Sadman Sakib, Lalit Kaurani, Robert Epple, Hauke B. Werner, Samy Hakroush, Julia Kitz, Marco Prinz, Eva Bartok, Gunther Hartmann, Simone Schröder, Peter Rehling, “..”  (2021)
Published 11. November 2021

Nat Com

https://doi.org/10.1038/s41467-021-26880-x

Publication

Heterogeneity of glutamatergic synapses: cellular mechanisms and network consequences

Carolin Wichmann, Thomas Kuner (2021)
Published 2. November 2021

Phys Rev

https://doi.org/10.1152/physrev.00039.2020

Publication

Photoactivatable Fluorescent Dyes with Hydrophilic Caging Groups and Their Use in Multicolor Nanoscopy

Alexey N. Butkevich, Michael Weber, Angel R. Cereceda Delgado, Lynn M. Ostersehlt, Elisa D’Este, Stefan W. Hell (2021)
Published 29. October 2021

ACS Pub

https://doi.org/10.1021/jacs.1c09999

Publication

Munc13-1 is a Ca(2+)-phospholipid-dependent vesicle priming hub that shapes synaptic short-term plasticity and enables sustained neurotransmission

Noa Lipstein, Shuwen Chang, Kun-Han Lin, Francisco Jose Lopez-Murcia, Erwin Neher, Holger Taschenberger, Nils Brose (2021).

Published 26. October 2021

Neuron

https://doi.org/10.1016/j.neuron.2021.09.054

Publication

Optimal Precision and Accuracy in 4Pi-STORM using Dynamic Spline PSF Models

Mark Bates, Jan Keller-Findeisen, Adrian Przybylski, Andreas Hüper, Till Stephan, Peter Ilgen, Angel R. Cereceda Delgado, Elisa D’Este, Stefan Jakobs, Steffen J. Sahl, Stefan W. Hell (2021)
Published 19. October 2021

BioRixV
https://doi.org/10.1101/2021.10.19.464803

now published 16. May 2022, Nat Meth
http://dx.doi.org/10.1038/s41592-022-01465-8

Publication

A microRNA signature that correlates with cognition and is a target against cognitive decline

Md Rezaul Islam, Lalit Kaurani, Tea Berulava, Urs Heilbronner, Monika Budde, Tonatiuh Pena Centeno, Vakthang Elerdashvili, Maria-Patapia Zafieriou, Eva Benito, Sinem M Sertel, Maria Goldberg, Fanny Senner, Janos L Kalman, Susanne Burkhardt, Anne Sophie Oepen, Mohammad Sadman Sakib, Cemil Kerimoglu, Oliver Wirths, Heike Bickeböller, Claudia Bartels, Frederic Brosseron […] Andre Fischer (2021)

Published 11. October 2021

Embo mol

https://doi.org/10.15252/emmm.202013659

Publication

Exercise as a model to identify microRNAs linked to human cognition: a role for microRNA-409 and microRNA-501

Maria Goldberg, Md Rezaul Islam, Cemil Kerimoglu, Camille Lancelin, Verena Gisa, Susanne Burkhardt, Dennis M. Krüger, Till Marquardt, Berend Malchow, Andrea Schmitt, Peter Falkai, Farahnaz Sananbenesi, Andre Fischer (2021)
Published 8. October 2021

Trans Psych

https://doi.org/10.1038/s41398-021-01627-w

Publication

The mammalian rod synaptic ribbon is essential for Cavchannel facilitation and ultrafast synaptic vesicle fusion

Chad Grabner, Tobias Moser (2021)
Published 7. October 2021

eLife

https://doi.org/10.7554/elife.63844

Publication

Bias-invariant RNA-sequencing metadata annotation

Hannes Wartmann, Sven Heins, Karin Kloiber, Stefan Bonn (2021)
Published 22. September 2021

GiGa Sci

http://dx.doi.org/10.1093/gigascience/giab064

Publication

Cellular Prion Protein Mediates α-Synuclein Uptake, Localization, and Toxicity In Vitro and In Vivo

Tobias Thom, Matthias Schmitz, Anna-Lisa Fischer, Angela Correia, Susana Correia, Franc Llorens, Anna-Villar Pique, Wiebke Möbiu, Renato Domingues, Saima Zafar, Erik Stoops, Christopher J. Silva, Andre Fischer, Tiago F. Outeiro, Inga Zerr (2021)
Published 27. August 2021

Mov Disord

http://dx.doi.org/10.1002/mds.28774

Publication

Tubular microdomains of Rab7-endosomes retrieve TrkA, a mechanism disrupted in Charcot-Marie-Tooth 2B

Ronja Markworth, Vivian Dambeck, Lars Malte Steinbeck, Angeliki Koufali Bastian Bues, Tal M. Yankovich, Carolin Wichmann, Katja Burk (2021)
Published 23. August 2021

J Cell Sci

https://doi.org/10.1242/jcs.258559

Publication

Surface tension and viscosity of protein condensates quantified by micropipette aspiration

Huan Wang, Fleurie M. Kelley, Dragomir Milovanovic, Benjamin S. Schuster, Zheng Shi (2021)
Published 30. July 2021

Biophys Rep

http://dx.doi.org/10.1016/j.bpr.2021.100011

Publication

Alpha-synuclein research: defining strategic moves in the battle against Parkinson’s disease

Luis M. A. Oliveira, Thomas Gasser, Robert Edwards, Markus Zweckstetter, Ronald Melki, Leonidas Stefanis,Hilal A. Lashuel, David Sulzer, Kostas Vekrellis, Glenda M. Halliday, Julianna J. Tomlinson, Michael Schlossmacher,Poul Henning Jensen, Julia Schulze-Hentrich, Olaf Riess, Warren D. Hirst, Omar El-Agnaf,Brit Mollenhauer, Peter Lansbury, Tiago F. Outeiro (2021)
Published 26. July 2021

npj Parkinsons Dis

http://dx.doi.org/10.1038/s41531-021-00203-9

Publication

Common molecular mechanisms underlie the transfer of alpha-synuclein, Tau and huntingtin and modulate spontaneous activity in neuronal cells

Inês Caldeira Brás, Mohammad Hossein Khani, Eftychia Vasili, Wiebke Möbius, Dietmar Riedel, Iwan Parfentev, Ellen Gerhardt, Christiane Fahlbusch, Henning Urlaub, Markus Zweckstetter,Tim Gollisch, Tiago Fleming Outeiro (2021)
Published 19. July 2021

BioRxiv

http://dx.doi.org/10.1101/2021.07.18.452825

Publication

Allosteric transcription stimulation by RNA polymerase II super elongation complex

Ying Chen, Seychelle M. Vos, Christian Dienemann, Momchil Ninov, Henning Urlaub, Patrick Cramer (2021)
Published 14. July 2021

Mol Cell

http://dx.doi.org/10.1016/j.molcel.2021.06.019

Publication

A large-scale nanoscopy and biochemistry analysis of postsynaptic dendritic spines

Martin S. Helm, Tal M. Dankovich, Sunit Mandad, Burkhard Rammner, Sebastian Jähne, Vanessa Salimi, Christina Koerbs, Richard Leibrandt, Henning Urlaub, Thomas Schikorski, Silvio O. Rizzoli (2021)
Published 24. June 2021

Nat NeuroSci

https://doi.org/10.1038/s41593-021-00874-w

Publication

Low-Expressing Synucleinopathy Mouse Models Based on Oligomer-Forming Mutations and C-Terminal Truncation of α-Synuclein

Ana Martinez Hernandez, Ivan Silbern, Insa Geffers, Lars Tatenhorst, Stefan Becker, Henning Urlaub, Markus Zweckstetter, Christian Griesinger, Gregor Eichele (2021)
Published 17. June 2021

Front NeuroSci

https://doi.org/10.3389/fnins.2021.643391

Publication

Evaluation and Optimization of High-Field Asymmetric Waveform Ion-Mobility Spectrometry for Multiplexed Quantitative Site-Specific N-Glycoproteomics

Pan Fang, Yanlong Ji, Ivan Silbern, Rosa Viner, Thomas Oellerich,  Kuan-Ting Pan*, Henning Urlaub (2021) 
Published 16. June 2021

ACS Pub

https://doi.org/10.1021/acs.analchem.1c00802

Publication

Alpha-synuclein induces epigenomic dysregulation of glutamate signaling and locomotor pathways

Samantha L. Schaffner, Zinah Wassouf, Diana F. Lazaro, Mary Xylaki, Nicole Gladish, David T. S. Lin, Julia MacIsaac, Katia Ramadori, Julia M. Schulze-Hentrich, Tiago F. Outeiro, Michael S. Kobor (2021)
Published 12. June 2021

BioRxiv

http://dx.doi.org/10.1101/2021.06.12.448150

Publication

Stable but not rigid: Chronic in vivo STED nanoscopy reveals extensive remodeling of spines, indicating multiple drivers of plasticity

Heinz Steffens, Alexander C. Mott , Siyuan Li, Waja Wegner, Pavel Švehla, Vanessa W. Y. Kan, Fred Wolf, Sabine Liebscher, Katrin I. Willig (2021)
Published 9. June 2021

Sci Adv

https://doi.org/10.1126/sciadv.abf2806

Publication

Resolving the molecular architecture of the photoreceptor active zone by MINFLUX nanoscopy

Chad P. Grabner, Isabelle Jansen, Jakob Neef, Tobias Weiss, Roman Schmidt, Dietmar Riedel, Christian A. Wurm, Tobias Moser (2021)
Published 30. May 2021

BioRxiv

http://dx.doi.org/10.1101/2021.05.28.446138

Publication

Gold-Conjugated Nanobodies for Targeted Imaging Using High-Resolution Secondary Ion Mass Spectrometry

Paola Agüi-Gonzalez, Tal M. Dankovich, Silvio O. Rizzoli, Nhu T. N. Phan (2021)
Published 28. May 2021
Preprints

http://dx.doi.org/10.20944/preprints202105.0687.v1

now published 10. July 2021, DMPI NanoMat
https://doi.org/10.3390/nano11071797

Publication

Correlative fluorescence microscopy, transmission electron microscopy and secondary ion mass spectrometry (CLEM-SIMS) for cellular imaging

Felix Lange, Paola Agüi-Gonzalez, Dietmar Riedel, Nhu T.N. Phan, Stefan Jakobs, Silvio O. Rizzoli (2021)
Published 10. May 2021

BioRxiv

https://doi.org/10.1371/journal.pone.0240768

Publication

Relative Quantification of Phosphorylated and Glycosylated Peptides from the Same Sample Using Isobaric Chemical Labelling with a Two-Step Enrichment Strategy

Ivan Silbern, Pan Fang, Yanlong Ji, Lenz Christof, Henning Urlaub, Kuan-Ting Pan (2021)
Published 6. May 2021

Springer

https://doi.org/10.1007/978-1-0716-1024-4_14

Publication

Dysfunction of RAB39B-Mediated Vesicular Trafficking in Lewy Body Diseases

David J. Koss, Susanna Campesan, Flaviano Giorgini, Tiago F. Outeiro (2021)
Published 3. May 2021

Mov Disord

http://dx.doi.org/10.1002/mds.28605

Publication

Super-resolution microscopy informs on the molecular architecture of alpha-synuclein inclusions in model systems and in the human brain

Patrick Weish, Diana F. Lázaro, Luís Palmares, Patrícia I. Santos, Christine Stadelmann, Günter U. Höglinger, Silvio O. Rizzoli, Tiago F. Outeiro (2021)
Published 26. April 2021

BioRxiv

http://dx.doi.org/10.1101/2021.04.25.441304

Publication

Secondary Ion Mass Spectrometry Imaging Reveals Changes in the Lipid Structure of the Plasma Membranes of Hippocampal Neurons following Drugs Affecting Neuronal Activity

Paola Agüi-Gonzalez, Bao Guobin, Maria A. Gomes de Castro, Silvio O. Rizzoli, and Nhu T. N. Phan (2021)
Published 26. April 2021

ACS Chem NeuroSci

https://doi.org/10.1021/acschemneuro.1c00031

Publication

Ultrastructural maturation of the endbulb of Held active zones comparing wild-type and otoferlin-deficient mice

Anika Hintze, Mehmet Gültas, Esther A. Semmelhack, Carolin Wichman (2021)

Published 23. April 2021

I Sci

https://doi.org/10.1016/j.isci.2021.102282

Publication

Exploring new roles for actin upon LTP induction in dendritic spines

Mayte Bonilla-Quintana, Florentin Wörgötter (2021)

Published 29. March 2021

Sci Rep

https://doi.org/10.1038/s41598-021-86367-z

Publication

Synapsin Condensates Recruit alpha-Synuclein

Christian Hoffmann, Roberto Sansevrino, Giuseppe Morabito, Chinyere Logan, R. Martin Vabulas, Ayse Ulusoy, Marcelo Ganzella, Dragomir Milovanovic (2021)

Published 25. March 2021

J Mol Bio

http://dx.doi.org/10.1016/j.jmb.2021.166961

Publication

RIM-Binding Proteins Are Required for Normal Sound-Encoding at Afferent Inner Hair Cell Synapses

Stefanie Krinner, Friederike Predoehl, Dinah Burfeind, Christian Vogl, Tobias Moser (2021)

Published 23. March 2021

Front Mol

https://doi.org/10.3389/fnmol.2021.651935

Publication

RIM-Binding Protein 2 organizes Ca2+channel topography and regulates release probability and vesicle replenishment at a fast central synapse

Tanvi Butola, Theocharis Alvanos, Anika Hintze, Peter Koppensteiner, David Kleindienst, Ryuichi Shigemoto, Carolin Wichmann, Tobias Moser (2021)

Published 20 March 2021
BioRxiv
https://doi.org/10.1101/2021.03.20.435607

now published 15. November 2021, J Neuro Sci
https://doi.org/10.1523/JNEUROSCI.0586-21.2021

Publication

Challenges facing quantitative large-scale optical super-resolution, and some simple solutions

Tal M. Dankovich, Silvio O. Rizzoli (2021)

Published 19. March 2021

Sci Dir

https://doi.org/10.1016/j.isci.2021.102134

Publication

Presynaptic activity and protein turnover are correlated at the single-synapse level.

Sebastian Jähne, Fabian Mikulasch, Helge GH Heuer, Sven Truckenbrodt, Paola Agüi-Gonzalez, Katharina Grewe, Angela Vogts, Silvio O Rizzoli, Viola Priesemann (2021)

Published 16. March 2021

Cell Rep

https://doi.org/10.1016/j.celrep.2021.108841

Publication

Memory consolidation and improvement by synaptic tagging and capture in recurrent neural networks

Jannik Luboeinski, Christian Tetzlaff (2021)

Published 3. March 2021

Comm Bio

https://doi.org/10.1038/s42003-021-01778-y

Publication

Reproducing Asymmetrical Spine Shape Fluctuations in a Model of Actin Dynamics Predicts Self-organized Criticality.

Mayte Bonilla-Quintana, Florentin Wörgötter, Elisa D’Este, Christian Tetzlaff, Michael Fauth (2021)

Published 17. February 2021

Sci Rep

https://doi.org/10.1038/s41598-021-83331-9

Publication

Monitoring mitochondrial translation in living cells.

Roya Yousefi, Eugenio F Fornasiero, Lukas Cyganek, Julio Montoya, Stefan Jakobs, Silvio O Rizzoli, Peter Rehling, David Pacheu-Grau (2021)

Published 15. February 2021

EMBO Rep

https://doi.org/10.1016/j.celrep.2021.108841

Publication

Clonal expansion and activation of tissue-resident memory-like TH17 cells expressing GM-CSF in the lungs of patients with severe -19

Yu Zhao, Christoph Kilian, Jan-Eric Turner, Lidia Bosurgi, Kevin Roedl, Patricia Bartsch, Ann-Christin Gnirck, Filippo Cortesi, Christoph Schultheiss, Malte Hellmig,…+ 24, Stefan Bonn, Ulf Panzer, Nicola Gagliani, Christian F. Krebs (2021).

Published 12. February 2021

Sci Imm

http://dx.doi.org/10.1126/sciimmunol.abf6692

Publication

Protein phosphorylation in depolarized synaptosomes: Dissecting primary effects of calcium from synaptic vesicle cycling

Ivan Silbern, Kuan-Ting Pan, Maksims Fiosins, Stefan Bonn, Silvio O Rizzoli, Eugenio F Fornasiero, Henning Urlaub, Reinhard Jahn (2021)

Published 12. February 2021

Mol Cell Prot

https://doi.org/10.1016/j.celrep.2021.108841

Publication

The Coding and Small Non-coding Hippocampal Synaptic RNAome.

Robert Epple, Dennis Krüger, Tea Berulava, Gerrit Brehm, Momchil Ninov, Rezaul Islam, Sarah Köster, Andre Fischer (2021)

Published 10. February 2021
Springer
https://doi.org/10.1007/s12035-021-02296-y

corrected 12. March 2021
https://doi.org/10.1007/s12035-021-02349-2

Publication

Hippocampal neurons respond to brain activity with functional hypoxia

Umer Javed Butt, Agnes A. Steixner-Kumar, Constanze Depp, Ting Sun, Imam Hassouna, Liane Wüstefeld, Sahab Arinrad, Matthias R. Zillmann, Nadine Schopf, Laura Fernandez Garcia-Agudo, Leonie Mohrmann, Ulli Bode, Anja Ronnenberg, Martin Hindermann, Sandra Goebbels, Stefan Bonn, Dörthe M. Katschinski, Kamilla W. Miskowiak, Klaus-Armin Nave, Hannelore Ehrenreich (2021)

Published 9. February 2021

Mol Psych

http://dx.doi.org/10.1038/s41380-020-00988-w

Publication

The effect of polydispersity, shape fluctuations and curvature on small unilamellar vesicle small-angle X-ray scattering curves

Veronica Chappa, Yuliya Smirnova, Karlo Komorowski, Marcus Müller, Tim Salditt (2021)

Published 8. February 2021

JAC

http://dx.doi.org/10.1107/s1600576721001461ades

Publication

Sulthiame impairs mitochondrial function in vitro and may trigger onset of visual loss in Leber hereditary optic neuropathy

Marie-Christine Reinert, David Pacheu Grau, Claudia B. Catarino, Thomas Klopstock, Andreas Ohlenbusch, Michael Schittkowski, Ekkehard Wilichowski , Peter Rehling, Knut Brockmann (2021)

Published 4. February 2021

Orphanet J

https://doi.org/10.1186/s13023-021-01690-y

Publication

Cofilin pathology is a new player on α-synuclein-induced spine impairment in models of hippocampal synucleinopathy

Oliveira da Silva MI, Santejo M, Babcock IW, Magalhães A, Minamide LS, Castillo E Gerhardt E, Fahlbusch C, Swanson RA, Outeiro TF, Bamburg JR, Liz MA (2021)

Published 2. February 2021

BioRxiv

http://dx.doi.org/10.1101/2021.02.02.425931

Publication

Lipids, lysosomes and mitochondria: insights into Lewy body formation from rare monogenic disorders

Daniel Erskine, David Koss, Viktor I. Korolchuk, Tiago F. Outeiro, Johannes Attems, Ian McKeith (2021)

Published 30. January 2021

Acta Neuropath

http://dx.doi.org/10.1007/s00401-021-02266-7

Publication

Phagocyte-mediated synapse removal in cortical neuroinflammation is promoted by local calcium accumulation

Mehrnoosh Jafari, Adrian-Minh Schumacher, Nicolas Snaidero, +13, Fred Wolf, Mario Kreutzfeldt, Ruben Portugues, Doron Merkler, Thomas Misgeldm, Mattin Kerschensteiner (2021)

Published 25. January 2021

Nat Neuro

http://dx.doi.org/10.1038/s41593-020-00780-7

Publication

Spatial clustering of orientation preference in primary visual cortex of the large rodent agouti

Dardo N Ferreiro, Sergioe A Conde-Ocazionez, João H.N Patriota, Luã C. Souza, Moacir F Oliveira, Fred Wolf, Kerstin E Schmidt (2020)

Published 22. January 2021

I Sci

https://doi.org/10.1016/j.isci.2020.101882

Publication

Exploring early time points of vimentin assembly in flow by fluorescence fluctuation spectroscopy

Eleonora Perego, Sarah Köster (2021)

Published 19. January 2021

J Lab on a Chip

https://doi.org/10.1039/D0LC00985G

Publication

NanoSIMS observations of mouse retinal cells reveal strict metabolic controls on nitrogen turnover

Elisa A Bonnin, Eugenio F Fornasiero, Felix Lange, Christoph W Turck, Silvio O Rizzoli (2021)

Published 11. January 2021

BMC Molecular and Cell Biology

https://doi.org/10.1186/s12860-020-00339-1

Publication

Alpha-Synuclein Antibody Characterization: Why Semantics Matters

Tiago F. Outeiro (2021)

Published 7. January 2021

Mol Neurobiol

http://dx.doi.org/10.1007/s12035-020-02269-7

Publication

2021

A sensory cell diversifies its output by varying Ca2+ influx-release coupling among active zones

Özge D Özçete, Tobias Moser (2020)

Published 21. December 2020

EMBO J

https://doi.org/10.15252/embj.2020106010

Publication

Rho-Kinase Inhibition by Fasudil Modulates Presynaptic Vesicle Dynamics

Kim Ann Saal, Carmina Warth Pérez Arias, Anna‐Elisa Roser, Jan Christoph Koch, Mathias Bähr, Silvio O. Rizzoli, Paul Lingor (2020)

Published 20. December 2020

J Neurochem

https://doi.org/10.1111/jnc.15274

Publication

The mRNA-binding protein RBM3 regulates activity patterns and local synaptic translation in cultured hippocampal neurons

Sinem M. Sertel, Malena S. von Elling-Tammen, Silvio O. Rizzoli (2020)

Published 11. December 2020

J Neurosci

https://doi.org/10.1523/JNEUROSCI.0921-20.2020

Publication

Post-Translational Modifications Soften Vimentin IntermediateFilaments

Julia Kraxner, Charlotta Lorenz, Julia Menzel, Iwan Parfentev, Ivan Silbern, Manuela Denz, Henning Urlaub, Blanche Schwappach, Sarah Köster (2020)

Published 10. December 2020

Nanoscale

https://doi.org/10.1039/D0NR07322A

Publication

A minimalist model to measure interactions between proteins and synaptic vesicles

Eleonora Perego, Sofiia Reshetniak, Charlotta Lorenz, Christian Hoffmann, Dragomir Milovanović, Silvio O. Rizzoli, Sarah Köster (2020)

Published 3. December 2020

Scie Rep

https://doi.org/10.1038/s41598-020-77887-1

Publication

Spatial clustering of orientation preference in primary visual cortex of the large rodent agouti

Dardo N. Ferreiro, Sergio Conde-Ocazionez, João HN Patriota, Luã C Souza, Moacir F. Oliveira, Fred Wolf, Kerstin E. Schmidt (2020)

Published 1. December 2020

iSci

https://doi.org/10.1016/j.isci.2020.101882

Publication

The Coding and Small Non-coding Hippocampal Synaptic RNAome

Robert Epple, Dennis Krüger, Tea Berulava, Gerrit Brehm, Momchil Ninov, Rezaul Islam, Sarah Köster Andre Fischer (2020)

Published 28. November 2021
BioRxiv
http://dx.doi.org/10.1101/2020.11.27.401901

Now published 10. February 2021, Mol Neurobiology
https://doi.org/10.1007/s12035-021-02296-y

Publication

Synaptic activity and strength are reflected by changes in the post-synaptic secretory pathway

Clara-Marie Gürth, Tal Dankovich, Silvio O. Rizzoli, Elisa D’Este (2020)

Published 25. November 2020

Sci Rep

https://doi.org/10.1038/s41598-020-77260-2

Publication

Extracellular matrix remodeling through endocytosis and resurfacing of Tenascin-R

Tal M. Dankovich, Rahul Kaushik, Gabriel Cassinelli Petersen, Philipp Emanuel Giro, Hannah Abdul Hadi, Guobin Bao, Sabine Beuermann, Benjamin H. Cooper, Alexander Dityatev, Silvio O. Rizzoli (2020)

Published 12. November 2020
BioRxiv
https://doi.org/10.1101/2020.11.11.377515

now published 8. December 2021, Nat Comm
https://doi.org/10.1038/s41467-021-27462-7

Publication

Doxycycline inhibits α-synuclein-associated pathologies in vitro and in vivo

Antonio Dominguez-Meijide, Valeria Parrales, Eftychia Vasili, Florencia González-Lizárraga, Annekatrin König, Diana F. Lázaro, Annie Lannuzel, Stéphane Haik, Elaine Del Bel, Rosana Chehín, Rita Raisman-Vozari, Patrick P. Michel, Nicolas Bizat, Tiago F Outeiro (2020)

Published 7. November 2020
BioRxiv
http://dx.doi.org/10.1101/2020.11.06.371229

Now published 8. Januar 2021, Neurobiol Dis
http://dx.doi.org/10.1016/j.nbd.2021.105256

Publication

Neuroligin-2 dependent conformational activation of Collybistin reconstituted in supported hybrid membranes

Jonas Schäfer, Lucas Förster, Ingo Mey, Theofilos Papadopoulos, Nils Brose, Claudia Steinem (2020)

Published 30. October 2020
Version of record 13. January 2021

JBC

https://doi.org/10.1074/jbc.RA120.015347

Publication

Neuropathology of patients with COVID-19 in Germany: a post-mortem case series

Jakob Matschke, Marc Lütgehetmann, Christian Hagel, Jan P Sperhake, Ann Sophie Schröder, Carolin Edler, Herbert Mushumba, Antonia Fitzek, Lena Allweiss, Maura Dandri, Matthias Dottermusch, Axel Heinemann, Susanne Pfefferle, Marius Schwabenland, Daniel Sumner Magruder, Stefan Bonn, Marco Prinz, Christian Gerloff, Klaus Püschel, Susanne Krasemann, Martin Aepfelbacher, Markus Glatzel (2020)

Published 21. October 2020

Lancet Neuro

https://doi.org/10.1016/S1474-4422(20)30308-2

Publication

A streamlined pipeline for multiplexed quantitative site-specific N-glycoproteomics

Pan Fang, Yanlong Ji, Ivan Silbern, Carmen Doebele, Momchil Ninov, Christof Lenz, Thomas Oellerich, Kuan-Ting Pan, Henning Urlaub (2020)

Published 19. October 2020

Nat Commun

https://doi.org/10.1038/s41467-020-19052-w

Publication

Increased expression of myelin-associated genes in frontal cortex of SNCA overexpressing rats and Parkinson's disease patients.

Thomas Hentrich, Zinah Wassouf, Christine Ehrhardt, Eva Haas, James D Mills, Eleonora Aronica, Tiago F. Outeiro, Jeannette Hübener-Schmid, Olaf Riess, Nicolas Casadei, Julia M Schulze-Hentrich (2020)

Published 5. October 2020

Aging (Albany NY)

https://doi.org/10.18632/aging.103935

Publication

Quantitative Synaptic Biology: A Perspective on Techniques, Numbers and Expectations.

SofiiaReshetniak , Ruben Fernández-Busnadiego, Marcus Müller, Silvio O. Rizzoli SO, Christian Tetzlaff (2020)

Published 2. October 2020

Int J Mol Sci

https://doi.org/10.3390/ijms21197298

Publication

Ultrastructural Imaging of Activity-Dependent Synaptic Membrane-Trafficking Events in Cultured Brain Slices

Cordelia Imig, Francisco José López-Murcia, Lydia Maus L, Ines H. García-Plaza, Lena S. Mortensen, Manuela Schwark, Valentin Schwarze, Julie Angibaud, U. Valentin Nägerl , Holger Taschenberger, Nils Brose, Benjamin H. Cooper (2020)

Published 28. September 2020

Neuron

https://doi.org/10.1016/j.neuron.2020.09.004

Publication

RAB39B is redistributed in dementia with Lewy bodies and is sequestered within aβ plaques and Lewy bodies

David J. Koss, Odeta Bondarevaite, Sara Adams, Marta Leite, Flaviano Giorgini, Johannes Attems, Tiago F. Outeiro (2020)

Published 6. August 2020

Brain Pathol

http://dx.doi.org/10.1111/bpa.12890

Publication

TIPPING THE SCALES: PEPTIDE-DEPENDENT DYSREGULATION OF NEURAL CIRCUIT DYNAMICS IN ALZHEIMER’S DISEASE

Samuel S. Harris, Fred Wolf, Bart De Strooper, Marcel Aurel Busche (2020)

Published 5. August 2020

Neuron

https://doi.org/10.1016/j.neuron.2020.06.005

Publication

Developmental GABA polarity switch and neuronal plasticity in Bioengineered Neuronal Organoids

Maira-Patapia Zafeiriou, Guobin Bao, James Hudson, Rashi Halder, Alica Blenkle, Mari-Kristin Schreiber, Andre Fischer, Detlev Schild, Wolfram-H.Zimmermann

(2020)

Published 29. July 2020

Nat Commun

https://doi.org/10.1038/s41467-020-17521-w

Publication

Deep-learning-based cell composition analysis from tissue expression profiles

Kevin Menden, Mohamed Marouf, Sergio Oller, Anupriya Dalmia, Karin Kloiber, Peter Heutink, Stefan Bonn (2020)

Published 22. July 2020

Sci Adv

https://doi.org/10.1126/sciadv.aba2619

Publication

Local translation in synaptic mitochondria influences synaptic transmission

Roya Yousefi, Eugenio F. Fornasiero, Lukas Cyganek, Stefan Jakobs, Silvio O. Rizzoli, Peter Rehling, David Pacheu-Grau (2020)

Published 22. July 2020

BioRxiv

http://dx.doi.org/10.1101/2020.07.22.215194

Publication

The Role of Alpha-Synuclein and Other Parkinson’s Genes in Neurodevelopmental and Neurodegenerative Disorders

C. Alejandra Morato Torres, Zinah Wassouf, Faria Zafar, Danuta Sastre, Tiago F Outeiro, Birgitt Schüle (2020)

Published 13. July 2020
Preprints
http://dx.doi.org/10.20944/preprints202007.0334.v1

now published 10. August 2020, J Mol Sci
https://doi.org/10.3390/ijms21165724

Publication

Distinct mechanisms of over-representation of landmarks and rewards in the hippocampus

Sofiia Reshetniak, Jan-Eike Ußling, Eleonora Perego, Burkhard Rammner, Masaaki Sato, Kotaro Mizuta, Tanvir Islam, Masako Kawano, Yukiko Sekine, Takashi Takekawa, Daniel Gomez-Dominguez, Alexander Schmidt, Fred Wolf, Karam Kim, Hiroshi Yamakawa, Masamichi Ohkura, Min GooLee, Tomoki Fukai, Junichi Nakai, Yasunori Hayashi (2020)

Published 7. July 2020

Cell Reports

https://doi.org/10.1016/j.celrep.2020.107864

Publication

A comparative analysis of the mobility of 45 proteins in the synaptic bouton

Sofiia Reshetniak, Jan-Eike Ußling, Eleonora Perego, Burkhard Rammner, Thomas Schikorski, Eugenio F. Fornasiero, Sven Truckenbrodt, Sarah Köster, Silvio O. Rizzoli (2020).

Published 6. July 2020

EMBO J

https://doi.org/10.15252/embj.2020104596

Publication

A nanobody-based fluorescent reporter reveals human α-synuclein in the cell cyto-sol

Christoph Gerdes, Natalia Waal, Thomas Offner, Eugenio F Fornasiero, Nora Wender, Hannes Verbarg, Ivan Manzini, Claudia Trenkwalder, Brit Mollenhauer, Timo Strohäker, Markus Zweckstetter, Stefan Becker, Silvio O Rizzoli, Fitnat B. Basmanav, Felipe Opazo (2020).

Published 1. June 2020

Nat Commun

https://doi.org/10.1038/s41467-020-16575-0

Publication

PROTEIN TRAPPING LEADS TO ALTERED SYNAPTIC PROTEOSTASIS IN SYNUCLEINOPATHIES

Patricia D. Santos, Tiago F. Outerio (2020)

Published 13. May 2020

Febs J

https://doi.org/10.1111/febs.15364

Publication

X1INH, an improved next-generation affinity-optimized hydrazonic ligand, attenuates abnormal copper(i)/copper(ii)-α-Syn interactions and affects protein aggregation in a cellular model of synucleinopathy

Daphne S Cukierman, Diana F Lázaro, Pamela Sacco, Patricia R Ferreira, Renata Diniz , Claudio O Fernández, Tiago F Outeiro, Nicolas Rey (2020)

Published 11. May 2020

Dalton Trans

https://doi.org/10.1039/D0DT01138J

Publication

Circumvention of common labelling artefacts using secondary nanobodies

Shama Sograte-Idrissi, Thomas Schlichthaerle, Carlos Duque-Afonso, Mihai Alevra, Sebastian Strauss, Tobias Moser, Ralf Jungmann, Silvio O. Rizzoli, Felipe Opazo (2020)

Published 24. April 2020

Nanoscale

https://doi.org/10.1039/D0NR00227E

Publication

Vesicle adhesion in the electrostatic strong coupling regime studied by time-resolved small-angle x-ray scattering

Karlo Komorowski, Jannis Schaepper, Michael Sztucki, Lewis Sharpnack, Gerit Brehm, Sarah Köster, Tim Salditt (2020

Published 16. April 2020

Soft Matter

https://doi.org/10.1039/D0SM00259C

Publication

SUMOylation controls the neurodevelopmental function of the transcription factor Zbtb20

Silvia Ripamonti, Orr Schomroni, Jeong Seop Rhee, Kala Chowdhury, Olaf Jahn,  Klaus P Hellmann, Stefan Bonn, Nils Brose, Marilyn Tirard (2020)

Published 31. March 2020

Nanoscale

https://doi.org/10.1111/jnc.15008

Publication

An experimentally generated pep-tide database increases the sensitivity of XL-MS with complex samples

Iwan Parfentev, Sandra Schilbach, Patrick Cramer, Henning Urlaub H (2020)

Published 19. March 2020

J Proteomics

https://doi.org/10.1016/j.jprot.2020.103754

Publication

Ultrastructural Correlates of Presynaptic Functional Heterogeneity in Hippocampal Synapses

Lydia Maus, ChoongKu Lee, Bekir Altas, Sinem M. Sertel, Kirsten Weyand, Silvio O. Rizzoli, Jeong Seop Rhee, Nils Brose, Cordelia Imig, Benjamin H. Cooper (2020)

Published 17. March 2020

Sci Direct

https://doi.org/10.1016/j.celrep.2020.02.083

Publication

Modeling the Shape of Synaptic Spines by Their Actin Dynamics

Mayte Bonilla-Quintana, Florentin Wörgötter, Christian Tetzlaff, Michael Fauth (2020)

Published 10. March 2020

Front Synaptic Neuroscience

https://doi.org/10.3389/fnsyn.2020.00009

Publication

LIGHT MICROSCOPY OF MITOCHONDRIA AT THE NANOSCALE

Stefan Jakobs, Till Stephan, Peter Ilgen, Christian Brüser (2020)

Published 24. February 2020

Annu Rev BioPhys

https://doi.org/10.1146/annurev-biophys-121219-081550

Publication

Explainable Deep Learning for Augmentation of Small RNA Expression Profiles

Jelena Fiosina, Maksims Fiosins, Stefan Bonn (2020).

Published 6. February 2020

J of Comp Bio

https://doi.org/10.1089/cmb.2019.0320

Publication

Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors

Lin Luo, Mateusz C. Ambrozkiewicz, Fritz Benseler, Cui Chen, Emilie Dumontier, Susanne Falkner, Elisabetta Furlanis, Andrea M. Gomez, Naosuke Hoshina, Wei-Hsiang Huang, Mary Anne Hutchison, Yu Itoh-Maruoka, Laura A. Lavery, Wei Li, Tomohiko Maruo, Junko Motohashi , Emily Ling-Lin Pai, Kenneth A. Pelkey, Ariane Pereira, Thomas Philips, Jennifer L. Sinclair, Jeff A. Stogsdill, Lisa Traunmüller, Jiexin Wang, Joke Wortel, Wenjia You, Nashat Abumaria, Kevin T. Beier, Nils Brose, Harold A. Burgess, Constance L. Cepko, Jean-François Cloutie, Cagla Eroglu, Sandra Goebbels, Pascal S. Kaeser, Jeremy N. Kay, Wei L, Liqun Luo, Kenji Manda, Chris J. McBain, Klaus-Armin Nave, Marco A.M. Prado, Vania F. Prado, Jeffrey Rothstein, John L.R. Rubenstein, Gesine Saher, Kenji Sakimura, Joshua R. Sanes, Peter Scheiffele, Yoshimi Takai, Hisashi Umemori, Matthijs Verhage, Michisuke Yuzaki, Huda Yahya Zoghbi, Hiroshi Kawabe, Ann Marie Craig (2020)

Published 5. February 2020

Neuron

https:/doi.org/10.1016/j.neuron.2020.01.008

Publication

Kinetic coupling of the respiratory chain with ATP synthase, but not proton gradients, drives ATP production in cristae membranes

Alexandra Toth, Axel Meyrat, Stefan Stoldt, Ricardo Santiago, Dirk Wenzel, Stefan Jakobs , Christoph von Ballmoos, Martin Ott (2020)

Published 21. January 2020

PNAS

https://doi.org/10.1073/pnas.1917968117

Publication

Synucleinopathies: Where we are and where we need to go

Inês Caldeira Brás, Antonio Dominguez-Meijide, Ellen Gerhardt, David Koss, Diana F. Lázaro, Patrícia I. Santos, Eftychia Vasili, Mary Xylaki, Tiago Fleming Outeiro (2020)

Published 20. January 2020

J Neurochem

http://dx.doi.org/10.1111/jnc.14965

Publication

EDITORIAL: PROTEIN MISFOLDING AND SPREADING PATHOLOGY IN NEURODEGENERATIVE DISEASES

Diana F. Lázaro, Arianna Bellucci, Patrik Brundin, Tiago F. Outeiro (2020)

Published 17. January 2020

Front Mol Neurosci

https://doi.org/10.3389/fnmol.2019.00312

Publication

Leaflet-dependent distribution of PtdIns`{`4,5`}`P2 in supported model membranes

Jonas Schäfer, Jessica Nehls, Markus Schön, Ingo P. Mey, Claudia Steinem (2020)

Published 17. January 2020

Langmuir

https://doi.org/10.1162/netn_a_00086

Publication

MINFLUX NANOSCOPY DELIVERS 3D MULTICOLOR NANOMETER RESOLUTION IN CELLS

Klaus C. Gwosch, Jasmin K. Pape, Francisco Balzarotti, Philipp Hoess, Jan Ellenberg, Jonas Ries, Stefan W.Hell (2020)

Published 13. January 2020

Nat Methods

https://doi.org/10.1038/s41592-019-0688-0

Publication

Realistic in silico generation and augmentation of single-cell RNA-seq data using generative adversarial networks

Mohamed Marouf, Pierre Machart, Vikas Bansal, Christoph Kilian, Daniel S. Magruder, Christian F. Krebs, Stefan Bonn (2020)

Published 9. January 2020

Nat Comm

https://doi.org/10.1038/s41467-019-14018-z

Publication

2020

The long noncoding RNA neuroLNC regulates presynaptic activity by interacting with the neurodegeneration-associated protein TDP-43

Sarva Keihani, Verena Kluever, Sunid Mandad, Vikas Bansal, Rahman R, Elisabeth Fritsch, Lucas Caldi Gomes, Annette Gärtner, Kügler S, Henning Urlaub, Jonathan D. Wren, Stefan Bonn, Silvio O. Rizzoli, Eugenio F. Fornasiero (2019)

Published 18. December 2019

Scie Adv

https://doi.org/10.1126/sciadv.aay2670

Publication

Mechanisms of alpha-synuclein toxicity: An update and outlook

Inês Caldeira Brás, Mary Xylaki, Tiago F. Outeiro (2019)

Published 23. November 2019

Porg Brain Res.

https://doi.org/10.1016/bs.pbr.2019.10.005

Publication

A mass spectrometry workflow for measuring protein turnover rates in vivo

Mihai Alevra, Sunit Mandad, Till Ischebeck, Henning Urlaub, Silvio O. Rizzoli*, Eugenio F. Fornasiero (2019) * corresponding author

Published 4. November 2019

Nat Protoc

https://doi.org/10.1038/s41596-019-0222-y

Publication

Are genetic and idiopathic forms of Parkinson's disease the same disease?

Leonor Correia Guedes, Tiago Mestre, Tiago F. Outeiro, Joaquim J. Ferreira (2019)

Published 23. October 2019

J Neurochem

https://doi.org/10.1111/jnc.14902

Publication

A combined miRNA-piRNA signature to detect Alzheimer's disease

Gaurav Jain, Anne Stuendl, Pooja Rao, Tea Berulava, Tonatiuh Pena Centeno, Lalit Kaurani, Susanne Burkhardt, Ivana Delalle, Johannes Kornhuber, Michael Hüll, Wolfgang Maier, Oliver Peters, Hermann Esselmann, Claudia Schulte, Christian Deuschle, Mathis Synofzik, Jens Wiltfang, Brit Mollenhauer, Walter Maetzler, Anja Schneider, Andre Fischer (2019)

Published 7. October 2019

Trans Psychiatry

https://doi.org/10.1038/s41398-019-0579-2

Publication

Synuclein Meeting 2019: where we are and where we need to go

Tiago F. Outeiro, Tiago A. Mestre (2019)

Published 23. August 2019

J Neurochem

https://doi.org/10.1111/jnc.14825

Publication

Epigenetics of the Synapse in Neurodegeneration

Mary Xylaki, Benedict Atzler, Tiago F Outeiro (2019)

Published 23. August 2019

Curr Neurol Neurosci Rep

http://dx.doi.org/10.1007/s11910-019-0995-y

Publication

Interrogating Synaptic Architecture: Approaches for Labeling Organelles and Cytoskeleton Components

Sofiia Reshetniak, Silvio O. Rizzoli (2019)

Published 23. August 2019

Front Synaptic Neurosci

https://doi.org/10.3389/fnsyn.2019.00023

Publication

Tagger – A Swiss army Knife for multiomics to dissect cell type-specific mechanisms of gene expression in mice

Lech Kaczmarczyk, Vikas Bansal, Ashish Rajput, Raza-ur Rahman, Wiesław Krzyżak, Joachim Degen, Stefanie Poll, Martin Fuhrmann, Stefan Bonn, Walker Scot Jackson (2019)

Published 8. August 2019

 PLOS Biol

https://doi.org/10.1371/journal.pbio.3000374

Publication

A2A R-induced transcriptional deregulation in astrocytes: An in vitro study

Isabel Paiva, Kévin Carvalho, Patrícia Santos, Lucrezia Cellai, Maria Angeliki S. Pavlou, Gaurav Jain, Thorsten Gnad, Alexander Pfeifer, Didier Vieau, André Fischer, Luc Buée, Tiago F. Outeiro, David Blum (2019)

Published 22. July  2019

Glia

https://doi.org/10.1002/glia.23688

Publication

Correlative STED super-resolution light and electron microscopy on resin sections.

Christian A Wurm, Heinz Schwarz, Daniel C. Jans, Dietmar Riedel, Bruno M Humbel, Stefan Jakobs (2019)

Published 16. July  2019

J Phys D Appl Phys

https://doi.org/10.1088/1361-6463/ab2b31

Publication

Cytosolic Trapping of a Mitochondrial Heat Shock Protein Is an Early Pathological Event in Synucleinopathies

Éva M. Szegő, Antonio Dominguez-Meijide, Ellen Gerhardt, Anne-Katrin König, David J. Koss, WenLi, Raquel Pinho, Christiane Fahlbusch, Mary Johnson, Patricia Santos, Anna Villar-Piqué, Tobias Thom, Silvio O. Rizzoli, Matthias Schmitz, Jiayi Li, Inga Zerr, Johannes Attems, Olaf Jahn, Tiago F. Outeiro (2019)

Published 2. July 2019

Cell Rep

https://doi.org/10.1016/j.celrep.2019.06.009

Publication

LRRK2, alpha-synuclein, and tau: partners in crime or unfortunate bystanders?

Tiago F. Outeiro, Kirsten Harvey, Antonio Dominguez-Meijide, Ellen Gerhardt (2019)

Published 28. June 2019

Biochem Soc Trans

https://doi.org/10.1042/BST20180466

Publication

Live-cell STED microscopy of mitochondrial cristae

Till Stephan, Axel Roesch, Dietmar Riedel, Stefan Jakobs (2019)

Published 17. May 2019
BioRxiv
http://dx.doi.org/10.1101/640920

now published 27. August 2019, Sci Rep
https://doi.org/10.1038/s41598-019-48838-2

Publication

Deep Learning and Random Forest-Based Augmentation of sRNA Expression Profiles

Jelena Fiosina, Maksims Fiosins, Stefan Bonn (2019)

Published 9. May 2019

Lect notes Comp

http://dx.doi.org/10.1007/978-3-030-20242-2_14

Publication

SIMS imaging in neurobiology and cell biology

Paola Agüi-Gonzalez, Sebastian Jähne, Nhu T. Phan (2019)

Published 9. May 2019

JAAS

https://doi.org/10.1039/C9JA00118B

Publication

Translocator Protein Ligand Protects against Neurodegeneration in the MPTP Mouse Model of Parkinsonism

Jing Gong, Éva M. Szego, Andrei Leonov, Eva Benito, Stefan Becker, Andre Fischer, Markus Zweckstetter, Tiago Outeiro, Anja Schneider (2019)

Published 8. May 2019

J Neurosci

https://doi.org/10.1523/JNEUROSCI.2070-18.2019

Publication

A theoretical framework to derive simple, firing-rate-dependent mathematical models of synaptic plasticity

Janne Lappalainen, Juliane Herpich, Christian Tetzlaff (2019)

Published 8. May 2019

Front Comp Neuroscie

https://doi.org/10.3389/fncom.2019.00026

Publication

Principles underlying the input-dependent formation and organization of memories

Juliane Herpich, Christian Tetzlaff (2019)

Published 1. Mai 2019

Netw. Neurosci

https://doi.org/10.1162/netn_a_00086

Publication

Nanomachinery Organizing Release at Neuronal and Ribbon Synapses

Rituparna Chakrabarti, Carolin Wichmann (2019)

Published 30. April 2019

Int J Mol Sci

https://doi.org/10.3390/ijms20092147

Publication

Neuronal Redox-Imbalance in Rett Syndrome Affects Mitochondria as Well as Cytosol, and Is Accompanied by Intensified Mitochondrial O2 Consumption and ROS Release

Karolina Can, Christiane Menzfeld, Lena Rinne, Peter Rehling, Sebastian Kügler, Gocha Golubiani, Jan Dudek, Michael Müller (2019)

Published 30. April 2019

Front Physiol

https://doi.org/10.3389/fphys.2019.00479

Publication

Fluorinated nanobodies for targeted molecular imaging of biological samples using nanoscale secondary ion mass spectrometry

Selda Kabatas, Paola Agüi-Gonzalez, Rena Hinrichs, Sebastian Jähne, Felipe Opazo, Ulf Diederichsen, Silvio O. Rizzoli, Nhu T. N. Phan (2019)

Published 24. April 2019

JAAS

https://doi.org/10.1039/C9JA00117D

Publication

Investigating targets for neuropharmacological intervention by molecular dynamics simulations

Giulia Rossetti, Achim Kless, Luhua Lai, Tiago F. Outeiro, Paolo Carloni (2019)

Published 23. April 2019

Biochem Soc Trans

http://dx.doi.org/10.1042/bst20190048

Publication

In vitro models of synucleinopathies: informing on molecular mechanisms and protective strategies

Amir Tayaranian Marvian, David J. Koss, Farhang Aliakbari, Dina Morshedi, Tiago F. Outeiro (2019)

Published 20. April 2019

J Neurochem

https://doi.org/10.1111/jnc.14707

Publication

The self-organized learning of noisy environmental stimuli re-quires distinct phases of plasticity

Steffen Krüppel, Christian Tetzlaff (2019)

Published 18. April 2019
BioRxiv
http://dx.doi.org/10.1101/612341

now published 1. March 2020, New Neuroscience
https://doi.org/10.1162/netn_a_00118

Publication

Correlating Synaptic Ultrastructure and Function at the Nanoscale

Lydia Maus, Bekir Altas, JeongSeop Rhee, Nils Brose, Cordelia Imig, Benjamin H. Cooper (2019)

Published 26. March 2019

BioRxiv

https://doi.org/10.1101/588848

Publication

Seeding variability of different alpha synuclein strains in synucleinopathies

Niccolò Candelise, Matthias Schmitz, Franc Llorens, Anna Villar‐Piqué, Maria Cramm, Tobias Thom, Susana Margarida da Silva Correia, José Eriton Gomes da Cunha, Wiebke Möbius, Tiago F. Outeiro, Valentina González Álvarez, Martina Banchelli, Cristiano D’Andrea, Marella de Angelis, Saima Zafar, Alberto Rabano, Paolo Matteini, Inga Zerr (2019)

Published 25. February 2019

Ann Neurol

https://doi.org/10.1002/ana.25446

Publication

A practical guide to optimization in X10 expansion microscopy

Sven Truckenbrodt, Christoph Sommer, Silvio O. Rizzoli, Johann G. Danzl (2019)

Published 18. February 2019

Nat Protoc

https://doi.org/10.1038/s41596-018-0117-3

Publication

Biasing the native α-synuclein conformational ensemble towards compact states abolishes aggregation and neurotoxicity

Anita Carija, Francisca Pinheiro, Jordi Pujols, Inês C. Brás, Diana Fernandes Lázaro, Carlo Santambrogio, Rita Grandori,Tiago F.Outeiro, Susanna Navarro, Salvador Ventura (2019)

Published 5. February 2019

Redox Biol

https://doi.org/10.1016/j.redox.2019.101135

Publication

Boron-Containing Probes for Non-optical High-Resolution Imaging of Biological Samples

Selda Kabatas, Paola Agüi‐Gonzalez, Kim‐Ann Saal, Sebastian Jähne, Felipe Opazo, Silvio O. Rizzoli, Nhu T. N. Phan (2019)

Published 7. January 2019

Angew Chem Int Ed Engl

https://doi.org/10.1002/anie.201812032

Publication

2019

Nanobodies reveal an extra-syn-aptic population of SNAP-25 and Syntaxin 1A in hippocampal neurons

Manuel Maidorn, Aurélien Olichon, Silvio O. Rizzoli, Felipe Opazo (2019)

Published 28. December 2018

MAbs

https://doi.org/10.1080/19420862.2018.1551675

Publication

Combined Use of Unnatural Amino Acids Enables Dual Color Super-Resolution Imaging of Proteins via Click Chemistry

Kim-A. Saal, Frank Richter, Peter Rehling, Silvio O. Rizzoli (2018)

Published 10. December 2018

ACS Nano

https://doi.org/10.1021/acsnano.8b06047

Publication

The role of LRRK2 in cell signaling

Kirsten Harvey, Tiago F. Outeiro (2019)

Published 19. November 2018

Chem Soc TRans

https://doi.org/10.1042/BST20180464

Publication

Sensing α-Synuclein From the Outside via the Prion Protein: Implications for Neurodegeneration

Inês Caldeira Brás, Luisa V. Lopes, Tiago F. Outeiro

Published 13. November 2018

Epub

https://doi.org/10.1002/mds.27478

Publication

Precisely measured protein lifetimes in the mouse brain reveal biologically-significant differences across tissues and subcellular fractions

Eugenio F. Fornasiero, Sunit Mandad, Hanna Wildhagen, Mihai Alevra, Burkhard Rammner, Sarva Keihani, Felipe Opazo, Inga Urban, Till Ischebeck, M. Sadman Sakib, Maryam K. Fard, Koray Kirli, Tonatiuh Pena Centeno, Ramon O. Vidal, Raza-Ur Rahman, Eva Benito, André Fischer, Sven Dennerlein, Peter Rehling, Ivo Feussner, Stefan Bonn, Mikael Simons, Henning Urlaub, Silvio O. Rizzoli (2018)

Published 12. October 2018

Nat Commun

https://doi.org/10.1038/s41467-018-06519-0

Publication

Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents de generation of dopaminergic neurons

Jordi Pujols, Samuel Peña-Díaz, Diana F. Lázaro, Francesca Peccati, Francisca Pinheiro, Danilo González, Anita Carija, Susanna Navarro, María Conde-Giménez, Jesús García, Salvador Guardiola, Ernest Giralt, Xavier Salvatella, Javier Sancho, Mariona Sodupe, Tiago Fleming Outeiro, Esther Dalfó, Salvador Ventura (2018)

Published 24. September 2018

PNAS

https://doi.org/10.1073/pnas.1804198115

Publication

Nuclear localization and phosphorylation modulate pathological effects of alpha-synuclein

Raquel Pinho, Isabel Paiva, Kristina Gotovac Jerčić, Luis Fonseca-Ornelas, Ellen Gerhardt, Christiane Fahlbusch, Paula Garcia-Esparcia, Cemil Kerimoglu, Maria A S Pavlou, Anna Villar-Piqué, Éva Szegő, Tomás Lopes da Fonseca, Francesca Odoardi, Szabolcs Soeroes, Ana Cristina Rego, Wolfgang Fischle, Jens C Schwamborn, Thomas Meyer, Sebastian Kügler, Isidre Ferrer, 
 Johannes Attems, André Fischer, Stefan Becker, Markus Zweckstetter, Fran Borovecki, Tiago F Outeiro (2018

Published 13. September 2018

Hum Mol Genet

https://doi.org/10.1093/hmg/ddy326

Publication

Circulating miRNAs as Diagnostic Biomarkers for Parkinson's Disease

Anna Elisa Roser, Lucas Caldi Gomes, Jonas Schünemann, Fabian Maass, Paul Lingor (2018)

Published 5. September 2018

Front Neuro Scie

https://doi.org/10.3389/fnins.2018.00625

Publication

Membrane binding, internalization, and sorting of alpha-synuclein in the cell

Caterina Masaracchia, Marilena Hnida, Ellen Gerhardt, Tomás Lopes da Fonseca, Anna Villar-Pique,Tiago Branco, Markus A. Stahlberg, Camin Dean, Claudio O. Fernández, Ira Milosevic & Tiago F. Outeiro (2018)

Published 14. August 2018

Acta Neuropathol Commun

https://doi.org/10.1186/s40478-018-0578-1

Publication

Alpha-synuclein deregulates the expression of COL4A2 and impairs ER-Golgi function

Isabel Paiva, Gaurav Jain, Diana F. Lázaro, Kristina Gotovac Jerčić, Thomas Hentrich, Cemil Kerimoglu, Raquel Pinho, Èva M. Szegő, Susanne Burkhardt, Vincenzo Capece, Rashi Halder, Rezaul Isla, Mary Xylaki, Lucas A. Caldi Gomes, Anna-Elisa Roser, Paul Lingor, Julia M. Schulze-Hentrich, Fran Borovečki, André Fischer, Tiago F. Outeiro (2018)

Published 6. August 2018

Cell Rep

https://doi.org/10.1016/j.nbd.2018.08.001

Publication

Robust nanoscopy of a synaptic protein in living mice by organic-fluorophore labeling

Jennifer-Magdalena Masch, Heinz Steffens, Joachim Fischer, Johann Engelhardt, Jasmine Hubrich, Jan Keller-Findeisen, Elisa D’Este, Nicolai T. Urban, Seth G. N. Grant, Steffen J. Sahl, Dirk Kamin, Stefan W. Hell (2018)

Published 6. August 2018

Proc Natl Acad Sci U S A

https://doi.org/10.1073/pnas.1807104115

Publication

X10 expansion microscopy enables 25-nm resolution on conventional microscopes

Sven Truckenbrodt, Manuel Maidorn, Dagmar Crzan, Hanna Wildhagen, Selda Kabatas, Silvio O. Rizzoli  (2018)

Published 10. July 2018

EMBO Rep

https://doi.org/10.15252/embr.201845836

Publication

Newly produced synaptic vesicle proteins are preferentially used in synaptic transmission

Sven Truckenbrodt, Abhiyan Viplav, Sebastian Jähne, Angela Vogts, Annette Denker, Hanna Wildhagen, Eugenio F.Fornasiero, Silvio O. Rizzoli (2018)

Published 27. June 2018

EMBO J

https://doi.org/10.15252/embj.201798044

Publication

SUMO1-conjugation is altered during normal aging but not by increased amyloid burden

Trayana Stankova, Lars Piepkorn, Thomas A. Bayer, Olaf Jahn, Marilyn Tirard (2018)

Published 6. April 2018

Aging Cell

https://doi.org/10.1111/acel.12760

Publication

WDR1 is a novel EYA3 substrate and its dephosphorylation induces modi-fications of the cellular actin cytoskeleton

Mihaela Mentel, Aura E. Ionescu, Ioana Puscalau-Girtu, Martin S. Helm, Rodica A. Badea, Silvio O. Rizzoli, Stefan E. Szedlacsek (2018)

Published 13. February 2018

Sci Rep

https://doi.org/10.1038/s41598-018-21155-w

Publication

2018

RIM-Binding Protein 2 Promotes a Large Number of CaV1.3 Ca2+-Channels and Contributes to Fast Synaptic Vesicle Replenishment at Hair Cell Active Zones

Stefanie Krinner, Tanvi Butola, SangYong Jung, Carolin Wichmann, Tobias Moser (2017)

Published 2. November 2017

Front Cell Neurosci

https://doi.org/10.3389/fncel.2017.00334

Publication

Piccolo Promotes Vesicle Replenishment at a Fast Central Auditory Synapse

Tanvi Butola, Carolin Wichmann, Tobias Moser (2017)

Published 25. October 2017

Front Synaptic Neurosci

https://doi.org/10.3389/fnsyn.2017.00014

Publication

2017